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Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.

Men's hair loss is caused by hormones and genes, and can be treated with medication and surgery, while graying is due to aging and has no prevention except dyeing.

Minoxidil effectively controls blood pressure but side effects may limit its use.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

Most patients with frontal fibrosing alopecia stabilized with treatment, especially younger ones, using intralesional corticosteroids and tacrolimus.

Pumpkin seed oil helps hair growth in men with hair loss.

High doses of finasteride cause cell growth and tumors in mice.

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.

St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Late pregnancy helps repair brain damage in rats due to the GABAergic system.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Oral ivermectin effectively cured scabies with minimal side effects, and finasteride promoted hair growth in men with hair loss.