Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that iodine deficiency, iodine excess, or the presence of antithyroid substances affected growth and behavior in Wistar rats, leading to various symptoms such as lethargy and alopecia.

This review discusses how dehydroepiandrosterone (DHEA) may exert its biological effects through multiple receptors and reports no new clinical results.

This study identified novel selective androgen receptor modulators with enhanced in vivo pharmacological activity through structure-activity relationship analysis in castrated rats.

This article explores how the integrated stress response and senescence-associated secretory phenotype influence stem cell fate decisions, highlighting their dual roles in both protecting and disrupting stem cell integrity.

This review discusses the potential of DHEAS and testosterone treatments to increase muscle mass in older men with sarcopenia, while effects on muscle function and physical performance remain unclear, and calls for further research on optimized approaches.

This study suggests that epitestosterone may play a role in regulating androgen-dependent processes like prostate growth and body hair distribution by counteracting testosterone's actions.

In this study, ELE was found to protect against oxidative stress-induced testosterone reduction in TM3 Leydig cells by increasing testosterone synthesis and decreasing its conversion.

In this study, daily administration of 100mg DHEA for 16 weeks in women with adequate ovarian reserve did not modify metabolic or reproductive variables, apart from increased antral follicular count and anti-Müllerian hormone levels.

This study found that cephalanthine inhibited the growth of gastric cancer cells in vitro and in vivo by inducing oxidative stress and altering energy metabolism, suggesting its potential as a treatment for gastric cancer.

This review highlights the significant risks posed by mercury to the endocrine system, including disruptions in hormone synthesis and regulation, stress response, and potential reproductive dysfunction, while noting the need for further research on dose-response relationships and long-term impacts.

This study used a glucocorticoid-injection model to mimic kidney-yang deficiency syndrome and reported symptoms related to hormonal imbalances in the hypothalamic-pituitary-target gland axes.

This review discusses differences in ERβ signaling between rodents and humans and reports no new clinical results; the authors highlight the need for further research in humans before using ERβ agonists clinically.

This study found that selenium deficiency in mice accelerated age-related conditions and metabolic decline but unexpectedly promoted longevity, suggesting low selenium levels might separate healthspan and lifespan.

In this rodent study, the researchers found that different hormone therapies affected gut microbiota and goblet cell counts, with notable microbial shifts observed between groups receiving estrogen with and without an orchiectomy, linked to estrogen metabolism.

This study found that brassinosteroid enhances kiwifruit root growth by regulating genes involved in auxin signal transduction, highlighting its critical role in root development.

In this case study, a woman with high 25(OH)D levels and persistent symptoms showed decreased parathormone after transdermal estrogen therapy, highlighting the importance of assessing both parathormone and estrogen levels in similar patients.

This study found that the L457(3.43)R mutation in the human luteinizing hormone receptor increases phosphodiesterase activity, reducing hormonal response despite elevated basal cAMP levels.

This review discusses the relevance of human androgen receptor action in sports doping and examines the potential of cell-based biological assays for detecting androgenic anabolic steroid use, without presenting new research findings.

This review discusses the role of neuroactive steroids in physiological processes and their potential involvement in neuropsychiatric disorders, but it reports no new experimental findings.

This article compiles evidence on prescribing estrogen for hormonal imbalance in women, emphasizing it should be personalized and carefully managed by healthcare providers based on individual cases.

Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.

This study suggested that moxibustion treatment before or at the early stage of diminished ovarian reserve in rats may improve ovarian function by modulating androgen balance, though its effects differ across intervention timings.

This study found that cold exposure disrupts the circadian rhythm in cultured human cells by reducing oscillation amplitude, which is restored upon rewarming, while human hair follicle cells showed minimal amplitude sensitivity to temperature changes, suggesting an evolutionary advantage related to Hopf bifurcation dynamics.

This review explores the applications of phytonutrient-based biosensors in micro-electrochemical systems and reports no new experimental findings, emphasizing the potential and challenges of this innovative approach.

This study suggests that selenium deprivation in mice accelerates age-related degeneration but paradoxically promotes longevity, potentially decoupling healthspan from lifespan.

This study found that switching juvenile mice from a high-fat, high-carbohydrate diet to a control diet optimally reduced hormonal imbalances and weight, with nutraceuticals offering partial support.

Histamine plays key roles in immune responses, stomach acid, and brain signals.

This study reported that applying natural or artificial folliculoid compounds to mouse skin caused estrous-like changes in internal sex organs, but did not lead to cancerous skin changes.

This paper reviews guidelines discussed at a meeting about research and practice themes, but reports no new research findings.