Search

everythinglearnresearchcommunity

for

Search:↓

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Nude mice with grafted human skin developed scars similar to human hypertrophic scars.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

CLE40 and CRN/CLV2 pathways have opposite effects on root growth in Arabidopsis.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.

The gene KAP22-1 affects wool yield and fiber shape in sheep.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Some hair loss disorders are caused by genetic mutations affecting hair growth.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.

Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.

A gene in Arabidopsis thaliana, AtPRPL1, affects root hair length but not cell wall composition.

The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.

ROXY proteins help plants respond to nitrate shortage by affecting nutrient sensing and growth.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.