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Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

Hair keratin-associated proteins are essential for strong hair, with over 80 genes showing specific patterns and variations among people.

AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

GLI2 increases follistatin production in human skin cells.

Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.

SCF and ET-1 together significantly increase skin pigmentation and melanin production.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

The formula YH0618 can reduce the harmful side effects of the chemotherapy drug Doxorubicin and protect healthy cells.

A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.

LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.

OCIAD2 and DCN genes affect hair growth in goats by having opposite effects on a growth signaling pathway and inhibiting each other.

The Ysc84/SH3yl1 protein family is important for cell movement and the process of taking in materials by interacting with actin and cell membranes.

The research linked PLCD1 gene variants to the development of trichilemmal cysts.

The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.

A Taiwanese patient had hair loss and skin bumps without the usual gene mutation, suggesting other genetic factors might be involved.

Many people diagnosed with androgenic alopecia might actually have hidden scarring or inflammation.

New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.

Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.