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research Hierarchical patterning modes orchestrate hair follicle morphogenesis
This study found that hair follicle patterning in development may arise from a combination of epidermal prepattern signals and mesenchymal self-organisation, with fibroblast growth factor and bone morphogenetic protein activities playing key roles.
research Cells within the bulge region of mouse hair follicle transiently proliferate during early anagen: heterogeneity and functional differences of various hair cycles
In this study, researchers found that bulge cells in mouse hair follicles undergo transient proliferation during early anagen, indicating their role as follicular stem cells. However, another factor beyond dermal papilla proximity may be required to initiate a new anagen phase.
research One-step generation of core–shell biomimetic microspheres encapsulating double-layer cells using microfluidics for hair regeneration
This study developed microfluidic-assisted GelMA-MSC/HAD-EPC microspheres that efficiently generated hair follicles in nude mice, suggesting a promising strategy for advancing hair-regenerative medicine.
research Generation and integration of hair follicle-primed spheroids in bioengineered skin constructs
This study found that incorporating hair follicle-primed spheroids into skin constructs showed potential for developing hair-bearing skin mimetics with follicle-forming abilities in vitro.
research Optimization of menthol-loaded nanocapsules for skin application using the response surface methodology
This study developed lipid-core nanocapsules for encapsulating menthol, improving its solubility and thermal stability, and demonstrated their safety and rapid skin absorption in ex vivo tests, highlighting potential applications for cosmeceuticals.
research Structure of intermediate filament assembly in hair deduced from hydration studies using small-angle neutron scattering
This study found that coconut oil impedes hair hydration more effectively than soybean oil by penetrating deeper, and suggested a new model for intermediate filament assembly in hair.
research How a Bird Gets Its Feathers: Insights from Chromatin Looping
This study observed that in chicken skin, large-scale differences in gene expression between feathered and scaly skin are controlled by enhancer-driven uniform expression, while small-scale differences within individual feathers are associated with chromatin looping.
research 881 Ionizing radiation triggers dedifferentiation of outer root sheath cells into stem cell-like progenitors for hair follicle regeneration
This study found that anagen hair follicles can quickly regenerate after radiation damage by forming new progenitor cells outside the bulge, bypassing the need for telogen entry.
research Ectopic olfactory receptors in human: New therapeutic possibilities
This review discusses the diverse functions and therapeutic potential of ectopic olfactory receptors throughout the body, emphasizing their roles in various cellular processes and potential in cancer detection and therapy, but reports no new clinical results.
research Effects of Solventson Spherical Crystals of Minoxidil
In this study, researchers investigated the formation of spherical crystals of minoxidil in various alcoholic solvents, discovering new types like spherulite aggregates and a unique butterfly-shaped crystal, with the spherulite aggregates showing improved powder flow properties compared to other forms.
research Bio-macromolecules/modified-halloysite composite hydrogel used as multi-functional wound dressing
This study found that a newly constructed composite hydrogel dressing, made from silk fibroin, chitosan, and halloysite, promoted hair follicle neogenesis, angiogenesis tissue regeneration, and scar reduction.
research Formulation and optimization of folate-bovine serum albumin-coated ethoniosomes of pterostilbene as a targeted drug delivery system for lung cancer: In vitro and in vivo demonstrations
The researchers reported that their novel formulation of pterostilbene-loaded ethoniosomes with folic acid coating effectively targeted lung cancer cells in vitro and demonstrated promising results in animal models, indicating potential for future targeted chemotherapy applications.
research Assembling Composite Dermal Papilla Spheres with Adipose-derived Stem Cells to Enhance Hair Follicle Induction
In this study, the researchers found that using a core-shell assembly of adipose-derived stem cells and dermal papilla cells reconstructed hair follicle cellular arrangements more effectively than mixed assemblies, enhancing hair formation in vivo.
research MLO-mediated Ca2+influx regulates root hair tip growth in Arabidopsis
This study found that the FER/MLO signaling module plays a crucial role in calcium oscillations and ROS production in root hair tip growth, with the MLO15 protein regulating these processes and restoring disrupted growth and signaling in fer mutant root hairs.
research Introduction to Hair-Follicle-Associated Pluripotent Stem Cells
This study found that hair-follicle-associated pluripotent stem cells can promote nerve repair and growth in a 3D culture model and potentially differentiate into cardiac muscle cells, offering advantages over other stem cell types for regenerative medicine.
research Herbal nano-formulations for topical delivery
This review explores research on nanoformulations for enhancing the topical delivery of herbal medicines, noting potential benefits like improved bioavailability and sustained delivery, and emphasizes the need for safety and toxicity guidelines in developing these novel drug delivery systems.
research Time and depth resolved visualisation of the diffusion of a lipophilic dye into the hair follicle of fresh unfixed human scalp skin
This study demonstrates that confocal laser scanning microscopy can effectively visualize the rapid diffusion and penetration pathway of a dye into the hair follicle in fresh human scalp skin.
research Description of the Intrafollicular Delivery of Large Molecular Weight Molecules to Follicles of Human Scalp Skin In Vitro
This study found that cationic lipid-based formulations enhanced the delivery of large molecules into hair follicles in human scalp skin, with potential to reach pharmacologically active concentrations in the hair bulb.
research Structure-activity relationship for calanthoside, a potential hairgrowth stimulant with an indole 2- S -,3- O -bis-glucoside structure. Part 1: Role of two glucoside moieties in promoting HFDPC proliferation
This study notes the ongoing challenge in developing new drugs for androgenetic alopecia, mentioning that both minoxidil and finasteride were originally intended for treating hypertension. Results are not reported.
research Evolutionary Trees of Intermediate Filament Proteins
research Circle hairs involving the extremities in a young girl
This report discusses the characteristics of circle hairs, a type of body hair growth disorder, and emphasizes the value of trichoscopy for diagnosis.
research Improved humoral immunity and protection against influenza virus infection with a 3D porous biomaterial vaccine
This study reported that an injectable hydrogel microparticle vaccine platform enhanced antibody responses and protection against influenza in mice, outperforming the traditional adjuvant aluminum hydroxide.
research 17-Hydroxyprogesterone Responses to Gonadotropin-Releasing Hormone Disclose Distinct Phenotypes of Functional Ovarian Hyperandrogenism and Polycystic Ovary Syndrome
This study found that women with PCOS who have an exaggerated 17-hydroxyprogesterone response to buserelin exhibit more severe hyperandrogenemia, increased insulin secretion, and reduced insulin sensitivity.
research Human hair follicle cells of outer root sheath maintain their genuine keratin expression in vitro
research COMPATIBILITY OF BIOMAGNETIC PROFILES FOUND IN LIVING MATTER BY CROSS SPECIES DEMONSTRATION
This review discusses the history and evolution of techniques for detecting bioelectromagnetic emissions from living tissues, exploring potential medical applications, but does not present new experimental results.
research HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression
This study demonstrated that HOXC13 directly influences hair keratin gene expression by binding to specific DNA motifs, suggesting its role in early hair follicle differentiation.
research There and Back Again: Hair Follicle Stem Cell Dynamics
This study reveals that stem cell descendants in mouse hair follicles can return to their niche to retain stemness and function as primary stem cells for future hair cycles.
research Microscopy‐guided laser ablation for the creation of complex skin models with folliculoid appendages
This study demonstrates the use of microscopy-guided laser ablation to create a highly structured 3D hydrogel-based organotypic skin model with folliculoid structures, potentially useful for studying hair follicle development or bioactive substance screening.
research Cell Viability and Hair Growth Effect on 3T3-L1 Cells of Ethanol Extract from Calendula officinalis L. Flower, Phellinus linteus Fruit Body and Houttuynia cordata Thunb. Whole Plant
This study found that 70% ethanol extract of Houttuynia cordata promoted hair growth in laboratory cell models, suggesting potential use in developing hair care products.