Search
for

    Did you mean Histone Deacetylases?
    Glossary Histone Deacetylases

    enzymes that remove acetyl groups from histone proteins

    Histone Deacetylases (HDACs) are enzymes that remove acetyl groups from histone proteins, leading to a more compact and less accessible form of DNA. This process can suppress gene expression by making it harder for transcription factors to access the DNA. HDACs play a crucial role in regulating gene activity and are involved in various biological processes, including cell cycle progression and differentiation.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Histone deacetylase inhibitors promote neurosteroid‐mediated cell differentiation and enhance serotonin‐stimulated brain‐derived neurotrophic factor gene expression in rat C6 glioma cells Journal of Neuroscience Research · 2009 · 35 citations
    2. Disrupted Ectodermal Organ Morphogenesis in Mice with a Conditional Histone Deacetylase 1, 2 Deletion in the Epidermis Journal of Investigative Dermatology · 2013 · 32 citations
    3. Sodium Valproate Improves Skin Flap Survival via Gamma-Aminobutyric Acid and Histone Deacetylase Inhibitory System 2019 · 8 citations
    4. Histone deacetylase 1 in patients with alopecia areata and acne vulgaris: An epigenetic alteration Australasian Journal of Dermatology · 2022 · 4 citations
    5. Nerve-mediated expression of histone deacetylases regulates limb regeneration in axolotls Developmental Biology · 2019 · 12 citations
    6. Stem cell-derived motor neurons from spinal and bulbar muscular atrophy patients Neurobiology of Disease · 2014 · 48 citations
    7. HDAC6-dependent deacetylation of NGF dictates its ubiquitination and maintains primordial follicle dormancy Theranostics · 2024
    8. Class IIa HDAC4 and HDAC7 cooperatively regulate gene transcription in Th17 cell differentiation Proceedings of the National Academy of Sciences · 2024 · 16 citations
    9. Epigenetic control of adult stem cell function Nature Reviews Molecular Cell Biology · 2016 · 179 citations
    10. The <i>hairless</i> gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor Genes & Development · 2001 · 178 citations
    11. Short-Chain Fatty Acids from <i>Cutibacterium acnes</i> Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes 2019 · 70 citations
    12. Susceptibility variants on chromosome 7p21.1 suggest HDAC9 as a new candidate gene for male-pattern baldness British Journal of Dermatology · 2011 · 51 citations
    13. Valproic acid promotes human hair growth in in vitro culture model Journal of Dermatological Science · 2013 · 48 citations
    14. Interactions of the Vitamin D Receptor with the Corepressor Hairless Journal of Biological Chemistry · 2007 · 42 citations
    15. TSA restores hair follicle-inductive capacity of skin-derived precursors Scientific Reports · 2019 · 18 citations
    16. Small RNAs Loom Large During Reprogramming Cell stem cell · 2011 · 18 citations
    17. Mapping of cis-acting expression quantitative trait loci in human scalp hair follicles BMC Dermatology · 2020 · 4 citations
    18. Second International Symposium—Epigenetic Regulation of Skin Regeneration and Aging: From Chromatin Biology towards the Understanding of Epigenetic Basis of Skin Diseases 2017 · 2 citations
    19. Genetics of Alopecia Encyclopedia of Life Sciences · 2012
    20. Analysis of hairless corepressor mutants to characterize molecular cooperation with the vitamin D receptor in promoting the mammalian hair cycle Journal of Cellular Biochemistry · 2010 · 22 citations
    21. Modulation of Vitamin D Receptor Activity by the Corepressor Hairless: Differential Effects of Hairless Isoforms Endocrinology · 2009 · 18 citations
    22. Inhibition of class I HDACs preserves hair follicle inductivity in postnatal dermal cells Scientific Reports · 2021 · 6 citations
    23. Hairless protein of Jumonji family and hair loss 2009
    24. Hairless: A nuclear receptor corepressor essential for skin function Advances in developmental biology · 2006
    25. Sirtuins pathways and redox homeostasis: a pilot study on young and old monozygotic twins Free Radical Biology and Medicine · 2015
    26. Valproic acid and alopecia: A two-edged sword Asian Journal of Psychiatry · 2017 · 2 citations
    27. Where WNT the Hair NEJM Journal Watch · 2013
    28. SIRT1 downregulation provokes immune-inflammatory responses in hair follicle outer root sheath cells and may contribute to development of alopecia areata Journal of Dermatological Science · 2023 · 13 citations
    29. Targeting cardiac hypertrophy through a nuclear co‐repressor EMBO molecular medicine · 2019 · 3 citations
    30. Intracellular protons accelerate aging and switch on aging hallmarks in mice Journal of cellular biochemistry · 2018 · 4 citations