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Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.

Loss of keratin K2 causes skin problems and inflammation.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.

Mice without certain skin proteins had abnormal skin and hair development.

Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.

Mice without the Sp6 gene have problems developing several body parts, including hair, teeth, limbs, and lungs.

Some babies are born with alopecia areata, and a treatment with clobetasol propionate can regrow hair in half of the cases.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.

The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.

People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.

Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.

Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.

BAF200 is essential for proper heart and coronary artery formation.

The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.

The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.