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Human leukocytes and beard hair follicle cells have internal daily clocks, and PER1 and PER3 genes may indicate individual circadian rhythms.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Ectodermal dysplasia causes various symptoms and early treatment is important for eye, dental, and skin issues.

Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

Eating paradise nuts led to selenium poisoning, causing nausea, hair loss, and other symptoms in two women.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

Different types of skin cells are organized in a special way in large wounds to help with healing and hair growth.

Syphilis has a wide range of symptoms that can look like other diseases, and if not treated, it can progress to a more serious stage, especially in HIV-positive patients.

CD98hc's role in skin health decreases with age.

Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.

Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.

Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

Trichoscopy is a useful method for identifying primary cicatricial alopecias and their specific types.

Pregnancy can change skin disease severity, with some conditions improving and others worsening, and treatment should balance benefits and fetal safety.

Etretinate treatment changed hair growth patterns in many patients.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.

Type I interferons play a key role in the development of various skin diseases.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Loss of keratin K2 causes skin problems and inflammation.

Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

Human placenta hydrogel helps restore cells needed for hair growth.

The conclusion is that CD90 is not a specific marker for fibroblast subtypes and better methods are needed to identify them.

BMP2 needs periosteal tissue to help regenerate mouse middle finger bones within a specific time.

Some people with heavy hair shedding might actually have a hidden form of alopecia, which can be identified by specific hair changes.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.