research The Expanding Significance of Keratin Intermediate Filaments in Normal and Diseased Epithelia
Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
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research Efficacy and Safety of Anti-Androgens in the Management of Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomised Controlled Trials
Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.
research Plumbagin, A Natural Compound With Several Biological Effects And Anti-Inflammatory Properties
Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.
research Keratin 79 Is a PPARA Target That Is Highly Expressed by Liver Damage
Keratin 79 is linked to liver damage and may help diagnose liver diseases.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Saw Palmetto Extract: A Dermatologist's Perspective
Saw palmetto extract may help with hair loss and acne but needs more research on safety and long-term effects.
research Schmallenberg Virus Infection Suspected in a Calf Born to an Imported Heifer
A calf in Scotland likely had Schmallenberg virus from its mother.
research Autotaxin-LPA Signaling Contributes to Obesity-Induced Insulin Resistance in Muscle and Impairs Mitochondrial Metabolism
Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.
research Testosterone and Doping Control
The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.
research 5α-Reductase Inhibitors Alter Steroid Metabolism and May Contribute to Insulin Resistance, Diabetes, Metabolic Syndrome, and Vascular Disease: A Medical Hypothesis
Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
research Glossary
research Regulatory Roles of Androgens in Cutaneous Wound Healing
Testosterone may slow down wound healing and increase inflammation.
research Metformin Therapy for the Reproductive and Metabolic Consequences of Polycystic Ovary Syndrome
Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.
research Hair-Root Changes in Andean Indian Children During Marasmic Kwashiorkor
Malnourished Andean Indian children had abnormal hair roots compared to healthy children.
research Polycystic Ovary Syndrome: A Common Reproductive and Metabolic Disorder Necessitating Early Recognition and Treatment
Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.
research Metformin Effects on Polycystic Ovarian Syndrome
Metformin may help regulate periods and cause modest weight loss in PCOS patients, but more research is needed.
research Polycystic Ovary Syndrome: Etiology, Pathogenesis, and Diagnosis
The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.
research Relationship Between Androgen Levels and Blood Pressure in Young Women With Polycystic Ovary Syndrome
High androgen levels in young women with PCOS are linked to higher blood pressure.
research Zinc: An Essential Trace Element for Parenteral Nutrition
Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.
research Adverse Reactions to Oral Retinoids: An Update
Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.
research Hair-Root Adaptation to Marasmus in Andean Indian Children
Children with marasmus have more resting hair follicles and thinner, less pigmented hair, showing long-term malnutrition.
research Hyperadrenocorticism (Cushing’s Disease or Syndrome) in Dogs: Treatment Approaches and Prognosis
Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.
research No Metabolic Impact of Surgical Normalization of Hyperandrogenism in Postmenopausal Women with Ovarian Androgen-Secreting Tumors
Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.
research Women's Health Care During the Perimenopause
The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.
research Iontophoretic Transdermal Delivery of Finasteride in Vesicular Invasomal Carriers
Finasteride delivery through skin improved using invasomes and iontophoresis.
research Niosomes as Carriers in Dermal Drug Delivery
Niosomes are a promising and effective way to deliver drugs through the skin.
research New Biomarkers to Evaluate Hyperandrogenemic Women and Hypogonadal Men
The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
research The Role of Cytochrome P-450 in Dermatology
Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.
research Medication Repurposing: New Uses for Old Drugs
Old drugs can be used for new treatments, saving time and money, but there are challenges like needing more evidence and legal concerns.
research Association of DNA Damage with Vitamin D and Hair Heavy Metals in Obese Women
Adequate vitamin D might lower, and high hair chromium might increase DNA damage in obese women.