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JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.

Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.

Using steroids can increase the risk of heart problems.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

Lower hair zinc and copper levels found in Turkish males with hair loss; higher BMI linked to less hair zinc.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

A male with aromatase deficiency improved bone health with estradiol treatment.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Manage hair shedding by identifying triggers, possibly using supplements or medications, and tracking with a health calendar.

High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Finasteride effectively treats hair loss in transgender men with few side effects.

Menopause affects hair and skin; more research needed for treatment.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

SVF-enhanced adipose transplantation shows potential as a hair loss treatment.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

The document concludes that treating tough skin disease in lupus involves sun protection, steroids, antimalarials, and various other therapies chosen based on individual risks and benefits.