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Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

A man with severe hair loss and skin disease regrew his hair with no side effects after taking tofacitinib.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Toxic Shock Syndrome mainly affects menstruating women, can recur, and is linked to staph bacteria, with rapid treatment being crucial.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Oestrogens are key for bone growth during puberty in both boys and girls.

Some medicinal plants can help heal wounds and may lead to new treatments.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

High androgen levels in young women with PCOS are linked to higher blood pressure.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Omeprazole effectively treats severe acid reflux in children for short-term use, but long-term safety needs more research.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Telogen effluvium is a common type of hair loss that can resolve on its own or become chronic, with treatment depending on early diagnosis.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.