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This review discusses how the nuclear lamina integrates biochemical and mechanical signals to influence gene expression and skin homeostasis, but reports no new clinical results.

This study introduced a new hair shading model that more accurately simulates light scattering on hair fibers, capturing effects not predicted by previous models.

This study reported detailed three-dimensional ultrastructural observations of human hair and hair follicles using a modified preparation method, including morphological differences in hair bulb cell layers and surface projections on root sheath cells.

New mutations in hair keratin genes cause the rare hair disorder monilethrix.

This study identified 15 Iranian patients with PLEC variants linked to various plectinopathies and highlighted a novel association between a homozygous nonsense variant in PLEC and a rare combination of disorders including EB pruriginosa, muscular dystrophy, and congenital myasthenic syndrome.

This chapter reviews the skin's structure and its clinical relevance, highlighting connective tissue diseases and the potential for novel treatments like protein, cell, or stem cell transfer, but reports no new findings.

In this study, rabbit esophageal epithelial cells were found to produce K4 and K13 keratins in suprabasal cells, forming disulfide-crosslinked dimers that may support the physical stability of the esophageal lining.

This study identified two novel point mutations in the hHb6 gene associated with monilethrix, suggesting these mutations could serve as diagnostic markers for this genetic hair disorder.

This study reported that human induced pluripotent stem cell-derived skin organoids, used to model epidermolysis bullosa, have an epidermal-dermal junction largely lacking type VII collagen, which is important for skin structure.

In this study, researchers developed enzymatic methods to isolate hair cuticle cells and remove the hair cuticle layer, finding that the harvested cuticle cells are thermally more stable and contain different structural proteins compared to descaled hair fibers.

In this study, researchers found that UV radiation causes hydroxy radicals to form cuticle holes specifically between the cuticle layers in wet hair, unlike random holes caused by Fenton's reaction.

This article discusses research about Netherton syndrome, highlighting its contributions to understanding epidermal structure, immune responses, and processes like atopic dermatitis, but it reports no new clinical findings.

This study reports new cellular features and complex interaction systems in fiber differentiation, indicating more intricate cellular organization than previously recognized, including features like mast cells and primary cilia.

This study found that hemoglobin α is upregulated in epidermal keratinocytes after UV exposure and may function as an antioxidant, particularly for hair follicle stem cells.

This study demonstrated that lactate dehydrogenase activity is notably high in quiescent hair follicle stem cells within mouse skin using a specific enzymatic activity assay.

This study found that basement membrane components and structures in mouse hair follicles are highly specialized for specific inter-tissue interactions, with laminin α5 playing a crucial role in hair cycle regulation and anchoring.

This study found that hair follicle matrix progenitors differentiate into various layers asynchronously, with early progenitors forming the companion layer and later progenitors generating the inner root sheath and hair shaft.

In this study, a new shading model for hair was developed that better matches real-life light scattering, thanks to detailed new measurements of hair fiber scattering not predicted by existing models.

This study found no significant histologic differences in skin structure based on age, sex, or woodchuck hepatitis virus infection status among woodchucks.

In this study, researchers conducted additional IHC staining on equine skin sections and found that collagen type III primarily labels the extracellular matrix, while anti-PDGFR-antibody staining highlights cells with long-shaped processes mainly arranged around hair follicles.

This study found that lead treatment enhances the imaging of organized hair lipid structures, revealing their orientation and possible composition as lead and calcium soaps, with potential applications in various fields.

This study found a novel R430Q gene mutation in hHb6, which may be linked to the hereditary hair disorder monilethrix in the examined family.

This study presented two cases of chronic hypervitaminosis A in adults, highlighting the first reported instance of hepatic cirrhosis due to long-term beef liver consumption.

Antiandrogens help manage PCOS symptoms but need careful monitoring.

This study suggests that higher use of phytoestrogen-containing hair and personal care products may increase the association between permanent hair dye, straightener use, and breast cancer risk in black women.

A young boy's uncombable hair is due to a rare genetic condition that usually improves over time.

In this case report, an 81-year-old male with chronic kidney disease developed cardiac tamponade while on minoxidil for hypertension, highlighting the rare but serious risk of pericardial effusion from this medication and emphasizing the need for vigilant monitoring, especially in vulnerable patients.

This review found that oral minoxidil, used for treating androgenetic alopecia, can cause dose-dependent fluid retention and weight gain, but remains safe for most patients; a diuretic might be needed if significant weight gain occurs.