May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study constructed a consensus single-cell atlas for hidradenitis suppurativa tunnels, identifying distinct fibro-inflammatory microenvironments with potential drug targets, suggesting TNF blockade alone may not be effective for all lesion types.
April 2023 in “Journal of Investigative Dermatology” 3D ultrasound can detect hair follicle changes and disease phases in alopecia areata.
1 citations
,
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed significant differences in the skin microbiome between hidradenitis suppurativa patients and healthy individuals, notably with decreased β-diversity and a distinct abundance of certain bacteria in affected skin.
22 citations
,
March 2021 in “Journal of Cutaneous Medicine and Surgery” This review discusses the integration of ultrasound in dermatology for improved lesion visualization and diagnosis, highlighting recent technological advancements like handheld devices and high-frequency probes, and reports no clinical results.
4 citations
,
January 2022 in “Australasian Journal of Dermatology” This study found that serum HDAC1 levels are significantly higher in patients with alopecia areata compared to those with acne vulgaris and healthy controls, suggesting potential therapeutic opportunities for HDAC inhibitors.
6 citations
,
January 2014 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” This case series describes three siblings with hereditary vitamin D-resistant rickets, highlighting variations in their clinical presentations.
2 citations
,
January 2019 in “Dermatologic Surgery” This overview describes the Dermatologic Surgery journal's extensive focus on peer-reviewed dermatologic surgery content, but it reports no new research findings.
2 citations
,
January 2015 in “Hair transplant forum international” This article discusses the introduction of human recombinant hyaluronidase in hair restoration surgery and presents no new clinical results.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study created a comprehensive single-cell atlas of hidradenitis suppurativa tunnels, identifying distinct microenvironmental endotypes linked to specific signaling pathways, suggesting that TNF blockade may not effectively address predominant pathways in many lesions and highlighting the potential for individualized treatment strategies.
31 citations
,
June 1997 in “International Journal of Dermatology” In this case report, a patient with Hodgkin's disease treated with ABVD chemotherapy became disease-free, and accompanying granuloma annulare skin lesions also improved.
28 citations
,
August 2003 in “Steroids” This study found that untreated hirsute patients have lower expression of type 2 17β-HSD mRNA in scalp hairs, indicating potential disturbances in androgen metabolism, compared to treated hirsute patients.
39 citations
,
August 2022 in “Cell Death and Disease” This study found that a dopamine-methacrylated hyaluronic acid hydrogel enhances the efficacy of adipose-derived stem cells in promoting skin regeneration, potentially involving the Notch signaling pathway.
238 citations
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July 2003 in “British Journal of Plastic Surgery” This review discusses the importance of early diagnosis and the management of hidradenitis suppurativa, reporting no new clinical results but highlighting current therapeutic approaches and need for collaboration in treatment.
January 2025 in “Diagnostics” This study found that a new three-dimensional high-frequency ultrasound (3D-HFUS) can successfully visualize skin tumors and inflammatory hair diseases, offering promising noninvasive diagnostic and evaluation capabilities compared to traditional two-dimensional methods.
1 citations
,
July 2007 in “Journal of Investigative Dermatology” The mutation causes hairless mice due to mislocalized and dysfunctional HR protein.
256 citations
,
March 2019 in “Journal of the American Academy of Dermatology” This review provides graded evidence and a therapeutic algorithm for managing hidradenitis suppurativa, but does not present new clinical results.
January 2024 in “Theranostics” This study found that HDAC6 plays a crucial role in regulating primordial follicle activation, with its overexpression delaying activation and preserving fertility by reducing NGF levels.
81 citations
,
July 2008 in “The Journal of Clinical Endocrinology and Metabolism” This study found that cortisone reductase deficiency is caused by inactivating mutations in the H6PD gene, affecting cortisol metabolism by preventing 11β-HSD1 enzyme function.
126 citations
,
October 1998 in “Experimental Dermatology” This review provides an overview of the hairless gene in mice and humans, discussing its structure, expression, and implications for understanding skin physiology and human disorders related to gene disruption, but it reports no new empirical findings.
36 citations
,
December 2014 in “F1000 prime reports” This article reviews the challenges in treating hidradenitis suppurativa and discusses potential treatment options, emphasizing the need for increased awareness and comprehensive care, but reports no new clinical results.
1 citations
,
October 2025 in “Journal of Clinical Medicine” In this systematic review, researchers reported that various types of laser therapy effectively treat hidradenitis suppurativa at different severity stages, with each laser offering specific benefits such as lesion removal, inflammation reduction, and improved quality of life.
90 citations
,
April 2013 in “Dermatology online journal” This article reviews various medical treatments for hidradenitis suppurativa based on the author's experience with over 350 patients, but it reports no new clinical findings.
4 citations
,
December 2024 in “JAAD Case Reports” This review discusses previously reported cases of drug-associated hidradenitis suppurativa linked to various immunomodulating medications but reports no new clinical results.
65 citations
,
January 2017 in “Postępy Dermatologii i Alergologii” This review highlights the increasing clinical applications of high-frequency ultrasonography in dermatology, particularly for assessing the depth of skin tumors and monitoring inflammatory skin diseases, but reports no new clinical results.
2 citations
,
May 2019 in “Journal of the American Academy of Dermatology” The correspondence discusses the higher prevalence of acne vulgaris in hidradenitis suppurativa patients, but notes potential overestimation due to unrecognized facial HS.
June 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses Hutchinson-Gilford Progeria Syndrome, its symptomatology, and the progress in developing treatment strategies, emphasizing that while a cure remains elusive, advances in understanding the disease's molecular mechanisms show promise for future approaches.
April 2021 in “Journal of Investigative Dermatology” This trial found that intradermal injections of the Hair Stimulating Complex were well-tolerated and effectively stimulated hair growth and prevented hair loss in male pattern baldness participants over 18 weeks.
This study utilized 3D ultra-high frequency ultrasound to effectively detect different disease phases of alopecia areata by visualizing hair follicle structures and identifying unique pathological signs, offering a promising non-invasive diagnostic tool that surpasses conventional methods.
48 citations
,
July 2023 in “Biomedicines” This review discusses transdermal drug delivery using hydrogel-forming microneedles and highlights their potential for disease treatment, but notes challenges in their clinical application.
4 citations
,
October 2021 in “Journal of Clinical Medicine” This study found that individuals with heterozygous truncation-type variants in the *DSP* gene exhibit lower skin temperature and higher transepidermal water loss, with specific microscopic skin changes and pseudomonilethrix.