October 2023 in “Research Square (Research Square)” This study developed a composite product from decellularized human placental connective tissue matrix and placental extract, finding that the combination showed improved biochemical and mechanical properties compared to each component alone, suggesting its potential use for treating chronic and deeper wounds.
May 2025 in “Journal of Craniofacial Surgery Open” This case study observed that high-intensity focused ultrasound treatment significantly improved hair density and reduced hair loss in a female patient with androgenetic alopecia, with no adverse events reported.
126 citations
,
October 1998 in “Experimental Dermatology” This review provides an overview of the hairless gene in mice and humans, discussing its structure, expression, and implications for understanding skin physiology and human disorders related to gene disruption, but it reports no new empirical findings.
April 2020 in “Journal of animal research” In this study, researchers identified hair follicle stem cells in the bulge region of canine hair follicles, suggesting potential applications for future translational research.
4 citations
,
July 2020 in “BMC Complementary Medicine and Therapies” This study suggests that human placenta treatment may promote hair regrowth in chemotherapy-induced alopecia by inhibiting apoptosis and encouraging hair follicle proliferation in a mouse model.
16 citations
,
April 2017 in “Journal of Cosmetic Dermatology” This study found that fig leaf extract significantly downregulated inflammatory and androgenic gene expression in vitro, suggesting potential topical benefits for certain skin disorders.
2 citations
,
September 2024 in “Journal of the American Academy of Dermatology” CCCA in African Americans may be linked to hair grooming, low vitamin D, and autoimmune factors.
1 citations
,
January 2001 in “Endocrine Practice” This study suggests that topical finasteride may benefit women with facial hirsutism, based on observations from a small sample.
30 citations
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April 1997 in “European journal of endocrinology” The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that skin organoids derived from iPSCs with an HS-associated NCSTN mutation showed defects in hair follicle stem cell differentiation and increased expression of inflammatory proteins related to hidradenitis suppurativa.
1 citations
,
December 1997 in “Journal of The European Academy of Dermatology and Venereology” In this study, 85.9% of 120 hirsute Saudi women exhibited elevated androgen levels, suggesting the need for a comprehensive hormonal evaluation to identify underlying causes of hirsutism.
January 2026 in “Dermatology Online Journal” This case report highlights that CCCA can present with multifocal patchy hair loss in younger men of African descent, suggesting the need for careful evaluation when diagnosing atypical alopecia patterns.
77 citations
,
February 2001 in “Journal of Dermatological Science” HGF activator helps convert HGF to its active form, promoting hair growth.
2 citations
,
March 2018 in “INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY” This case report describes a pregnant woman diagnosed with Cushing Syndrome, likely due to an adrenal tumor, whose condition worsened during hospitalization, resulting in heart failure, sepsis, and shock.
25 citations
,
September 2010 in “Journal of Cutaneous Medicine and Surgery” This study found that central centrifugal cicatricial alopecia primarily affects adult women of African descent and suggests an association with traumatic hair care practices and delayed diagnosis.
April 2024 in “Skin health and disease” In this case study, a patient developed parieto-temporal pain, tissue necrosis, and alopecia after receiving a hyaluronic acid injection for temporal augmentation, which was effectively treated with hyaluronidase and aspirin.
January 2025 in “JCEM Case Reports” In this case report, a 21-year-old woman diagnosed with ACTH-independent Cushing syndrome showed improvement in symptoms, including a more regular menstrual cycle and lower hirsutism, after starting treatment with ketoconazole, although she developed hypertension.
April 2019 in “Journal of the Endocrine Society” This case study reported that even with improved adrenal androgens and testosterone levels, treating women with AH-PCOS with glucocorticoids did not significantly improve ovulatory function or hirsutism.
33 citations
,
October 1996 in “Journal of Investigative Dermatology” July 2024 in “Journal of Investigative Dermatology” Sex and race affect immune responses and treatment outcomes in Hidradenitis suppurativa.
April 2016 in “Journal of Investigative Dermatology” This study suggests that lithocholic acid may enhance hair regeneration in alopecia by activating vitamin D receptors in human dermal papilla cells.
18 citations
,
October 2009 in “Endocrinology” This study demonstrated that both HR isoforms are expressed in keratinocytes, but HRDelta1072-1126 lacks corepressor activity and may act as a coactivator by inhibiting HDAC recruitment to the VDR transcriptional complex.
10 citations
,
April 2023 in “JAAD Case Reports” This article discusses the challenges in treating hidradenitis suppurativa, highlighting that adalimumab is currently the only FDA-approved treatment, and reports no clinical results.
5 citations
,
February 2017 in “Biomolecules & Therapeutics” The authors reported that 4-O-methylhonokiol decreased TGF-β1-induced cell cycle arrest and oxidative stress markers in human keratinocyte cells, suggesting a potential protective role in TGF-β1-mediated cell cycle regulation.
2 citations
,
October 2000 This report discusses a request for a health hazard evaluation at Equifax in St. Petersburg, Florida concerning potential workplace exposures related to reported employee health issues, particularly hair loss, but provides no new results.
May 2013 in “Hair transplant forum international” The article discusses a complication that occurred during a follicular unit extraction hair restoration procedure, presenting an opportunity for the author to learn from the experience and reports no new research findings.
September 2018 in “Cumhuriyet medical journal” This study found that women with severe hirsutism have thicker subcutaneous abdominal fatty tissue and are more likely to develop metabolic syndrome compared to those with moderate hirsutism.
67 citations
,
January 1997 in “Lancet” This article discusses the causes of hirsutism, identifying increased androgen production and heightened skin sensitivity, and provides no new clinical results.
September 2018 in “Journal of the American Academy of Dermatology” Elderly patients with CCCA were all African American with low vitamin D, but no iron or zinc deficiencies, and no hormonal imbalances compared to younger patients.
256 citations
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March 2019 in “Journal of the American Academy of Dermatology” This review provides graded evidence and a therapeutic algorithm for managing hidradenitis suppurativa, but does not present new clinical results.