July 2018 in “Elsevier eBooks” This chapter details the causes and diagnostic process of pediatric alopecia, including trichoscopic findings, but reports no new clinical results.
71 citations
,
November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses the role of Edar signaling in hair follicle development and cycling, emphasizing its impact on cell fate, differentiation, and interactions with other pathways, but reports no new results.
July 2021 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This article reports on a family with six members diagnosed with monilethrix, highlighting varying degrees of alopecia linked to this rare hair shaft defect.
92 citations
,
September 2019 in “ACS nano” This study observed that a wearable electric stimulation device significantly promoted hair regeneration in rats and mice, outperforming conventional pharmacological treatments and enhancing growth factor secretion.
68 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests a regulatory model where HOXC13 activates Foxn1, affecting hair and nail differentiation, supported by similarities in Hoxc13(tm1Mrc) and Foxn1(nu) mice phenotypes and gene expression patterns.
January 2024 in “International Journal of Advanced Research” This case report describes a 56-year-old woman with wooly hair and skin lesions, who experienced reduced plaque size and thickness after using 6% salicylic acid topically for three months.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that rare damaging variants in the KRT82 gene, which affect hair shaft integrity, may contribute to the risk of alopecia areata.
February 2019 in “International Journal of Dermatology and Clinical Research” In this study, Nε-(carboxymethyl) lysine was found to weaken hair follicle morphogenesis and inhibit essential cell activities in a model simulating accumulated glycation.
36 citations
,
July 1996 in “The journal of investigative dermatology/Journal of investigative dermatology” This research reports a new autosomal recessive mutation in mice, 'lanceolate hair', causing generalized alopecia and hair shaft abnormalities, which may serve as a model for Netherton's syndrome in humans.
24 citations
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August 2023 in “Journal of the American Academy of Dermatology” Trichoscopy helps diagnose and manage different types of hair loss effectively.
8 citations
,
March 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that weakened anchorage of hair shafts, associated with the abnormal expression of 14-3-3σ, may contribute to alopecia in Er/+ mice.
Loose anagen hair syndrome in children may improve with age, but treatment results vary.
7 citations
,
April 1996 in “British Journal of Dermatology” This study found that intermediate filaments and matrix proteins in presumptive hair shaft cells are synthesized sequentially, identifying a new polypeptide component that changes during hair cell differentiation.
This abstract provides contact information for Dr. Ban Kamoona at the Medical University – Sofia and contains no research findings.
42 citations
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September 2003 in “Journal of Investigative Dermatology” A missing mK6irs1 gene causes hair loss in mice.
October 2015 in “CRC Press eBooks” This review discusses alopecia classifications for diagnosis and prognosis but reports no new clinical findings.
26 citations
,
January 1983 in “PubMed” This study reports that despite normal cystine incorporation into hair follicles, trichothiodystrophy patients have decreased cystine levels in hair shafts, contradicting the hypothesis of defective transport in hair follicles.
68 citations
,
April 2012 in “Journal of Investigative Dermatology” The study reports that Fgf18 and Tgf-β2 signaling pathways in hair follicle stem cells have opposing effects on the timing of hair cycle transitions, influencing the shift from telogen to anagen phases.
3 citations
,
February 2016 in “Dermatologic Therapy” Using minoxidil and tretinoin on the skin, along with oral vitamin D, improved hair thickness and density in two girls with woolly hair.
This chapter reviews the clinical and morphological diagnostic features of various hair dysplasias, including atypical pili torti, pseudomonilethrix, and trichothiodystrophy, and reports no new results.
75 citations
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April 2000 in “Developmental Dynamics” This study suggests that the structural integrity and physical proximity of Whn's DNA binding and activation domains are crucial for hair keratin gene activation and may explain the nude phenotype.
13 citations
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November 2012 in “PLoS ONE” This study identified a novel recessive mutation in mice causing lethal congenital lamellar ichthyosis, with skin and hair follicle alterations similar to human congenital ichthyoses, linked to a specific genetic defect affecting Fatp4.
April 2017 in “IOSR journal of dental and medical sciences” This abstract discusses Netherton Syndrome, a genetic disorder with a characteristic triad of symptoms caused by SPINK5 gene mutation, and reports no new clinical findings or treatment advances.
October 2018 in “InTech eBooks” This research suggests that mouse mutants and genomics can help study hair biology and epithelial differentiation by focusing on the role of the Foxn1 gene.
38 citations
,
February 2016 in “Surgery Journal” This article discusses a wide range of procedures in facial plastic surgery and highlights the recent advancements and trends without reporting new clinical findings.
3 citations
,
June 2002 in “PubMed” This case report describes the diagnosis of Netherton's syndrome in two young sisters, attributing their serious erythrodermia, poor hair growth, and atopic conditions to this hereditary condition.
10 citations
,
May 2010 in “Journal of The American Academy of Dermatology” This report presents a rare case of short anagen syndrome in a 38-year-old African American woman, expanding the documented demographic beyond previously reported Caucasian individuals with fine blond hair.
44 citations
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March 2019 in “Experimental Dermatology” This study analyzed the cornified envelope of epidermal proteins, finding keratins dominate, which may help explain the minimal impact of deleting genes for single envelope components in congenital ichthyosis.
19 citations
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March 1988 in “International Journal of Dermatology” This paper reviews different types of hair shaft dysplasias and does not report any new clinical findings.
86 citations
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October 2013 in “Dermatologic Clinics” Trichoscopy is a useful non-invasive method for diagnosing different hair loss conditions.