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New treatments for male hypogonadism are effective and should be personalized.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Some medications can cause acne, and stopping these drugs is the main treatment.

Ice-skating athletes often have skin problems due to cold, infections, and inflammation, needing careful treatment and prevention.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Skin problems are common and important signs of eating disorders and treating the eating disorder can improve these skin conditions.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Some skin conditions look like acne but are caused by drugs, and they usually get better when the drug is stopped.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

Injection lipolysis effectively reduces small fat deposits and should be done with care and proper patient selection.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Improved dermabrasion techniques in 1987 led to better treatment results for skin issues like acne scars.

Eating disorders can cause skin problems that need treating the underlying condition for better health.

People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.

Rats had lasting erectile problems after stopping a certain medication.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Mesotherapy might help reduce fat in specific areas for those close to their ideal weight, but more research and care are needed to ensure safety.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

NFIC helps human dental stem cells grow and become tooth-like cells.