research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders
S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
Search
for
Sort by
Research
690-720 / 1000+ results 
research Repeated Finasteride Administration Induces Depression-Like Behavior in Adult Male Rats
Finasteride use can cause depression-like behavior in male rats.
research Increased Retinol-Binding Protein 4 and Anti-RBP4 Antibody in Alopecia Areata
People with alopecia areata have higher levels of RBP4 protein and antibodies against it.
research Evaluating Statistics in Clinical Trials: Making the Unintelligible Intelligible
Doctors need to understand statistics to properly evaluate clinical trials for patient care.
research Spironolactone Use and the Risk of Breast Cancer
Spironolactone use is not linked to an increased risk of breast cancer, but caution is advised for high-risk patients.
research Cancer
Some medications can improve skin conditions, while lifestyle factors like smoking and drinking may worsen them; treatments like monoclonal antibodies and imiquimod cream show promise for certain skin diseases.
research Psoriasis, Acne, and Disorders of Keratinization
Treating psoriasis with UVB light three times a week is faster than twice a week, and certain medications and lifestyle factors affect psoriasis treatment outcomes.
research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.
research Alopecia Areata: Genetic and Immunological Insights
Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.
research The C3H/HeJ Mouse and DEBR Rat Models for Alopecia Areata: Review of Preclinical Drug Screening Approaches and Results
Both mouse and rat models are effective for testing alopecia areata treatments.
research Determination of Protonation State in Molecular Salt of Minoxidil and 2,4-Dihydroxybenzoic Acid Through a Combined Experimental and Theoretical Study: Influence of Proton Transfer on Biological Activities
The MXD/24HA salt is more effective for hair growth than raw MXD.
research The 'Bald' Phenotype (Androgenetic Alopecia) Is Caused by the High Glycemic, High Cholesterol, and Low Mineral 'Western Diet'
Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.
research Treatment of Pseudofolliculitis in Trichotillomania Improves Outcome
Treating scalp issues in hair-pulling disorder helps hair regrow and reduces itch.
research The Germinative Epithelium of Sheep Vibrissae and Wool Follicles Has Extensive Proliferative Potential but Is Dependent on the Dermal Papilla
Sheep hair follicle cells can grow a lot but need the dermal papilla to do so.
research Dermatological Changes During Menopause and HRT: What to Expect
Menopause worsens skin, hair, and nails, affecting self-esteem and quality of life.
research Regenerating the Skin: A Task for the Heterogeneous Stem Cell Pool and Surrounding Niche
Different types of stem cells and their environments are key to skin repair and maintenance.
research Does Prostaglandin D2 Hold the Cure to Male Pattern Baldness?
Prostaglandin D₂ might be targeted for new male pattern baldness treatments.
research Susceptibility Variants on Chromosome 7p21.1 Suggest HDAC9 as a New Candidate Gene for Male-Pattern Baldness
A gene called HDAC9 might be a new factor in male-pattern baldness.
research Anatomy of the Ageing Face
The document concludes that understanding the anatomical changes of the ageing face is important for effective rejuvenation treatments.
research Cyberspace Chat: An Examination of the Potential Benefits of Caffeine, Niacinamide, and Panthenol
Caffeine, niacinamide, and panthenol may improve hair growth, fullness, and healing when applied to the scalp.
research Society News
Smoking doubles the risk of blindness, and physical exercise helps dyslexic children read better.
research A Comprehensive Review of Platelet-Rich Plasma for the Treatment of Dermatologic Disorders
Platelet-rich plasma can increase hair density and may help treat some skin conditions, but it's costly, not FDA-approved, and needs more research.
research The Steroidogenesis Inhibitor Finasteride Reduces the Response to Both Stressful and Rewarding Stimuli
Finasteride reduces response to stress and rewards, affecting behavior and mental health.
research Diagnostic Accuracy of Trichoscopy in Trichotillomania: A Systematic Review
Trichoscopy is a reliable method for diagnosing hair-pulling disorder.
research Frontal Fibrosing Alopecia: An Update on Pathogenesis, Diagnosis, and Treatment
The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.
research Cross-Species Sensitivity to a Novel Androgen Receptor Agonist of Potential Environmental Concern, Spironolactone
Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.
research The 5α-Reductase Inhibitor Finasteride Increases Suicide-Related Aggressive Behaviors and Blocks Clozapine-Induced Beneficial Effects in an Animal Model of Schizophrenia
Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.
research Gut Microbiome, Metabolome and Alopecia Areata
The health of the gut may be important in developing new ways to prevent, diagnose, and treat alopecia areata.
research Neuroactive Steroid Levels Are Modified in Cerebrospinal Fluid and Plasma of Post-Finasteride Patients Showing Persistent Sexual Side Effects and Anxious/Depressive Symptomatology
Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.
research The Post-Finasteride Syndrome: Clinical Manifestation of Drug-Induced Epigenetics Due to Endocrine Disruption
Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.