research Data from Synergistic Function of Smad4 and PTEN in Suppressing Forestomach Squamous Cell Carcinoma in Mice
Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.
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research Clinical Spectrum And Immunological Profile Of Patients With Mixed Connective Tissue Disease Presenting In A Tertiary Care Hospital
Early treatment of mixed connective tissue disease is crucial to prevent severe autoimmune conditions.
research Immunohistochemical Study Assessing Stem Cell Factor Receptor C-Kit in Patients with Alopecia
People with alopecia have shorter hair follicles and more c-kit, a stem cell factor receptor, which could predict how the condition progresses.
research CME Examination: Dermatology Case-Based Posttest on Lichen Planopilaris and Chronic Cutaneous Lupus Erythematosus
Control symptoms and use safe treatments for skin conditions like lichen planopilaris and chronic cutaneous lupus erythematosus.
research Association of Lichen Planopilaris with Seborrheic Dermatitis: A Retrospective Case-Control Study
People with lichen planopilaris often have seborrheic dermatitis, which can delay the diagnosis of lichen planopilaris.
research Two Cycles of ABVD Followed by Involved Field Radiotherapy with 20 Gray Is the New Standard of Care in the Treatment of Patients with Early Stage Hodgkin Lymphoma: Final Analysis of the Randomized German Hodgkin Study Group Trial HD10
Two cycles of ABVD chemotherapy followed by 20 Gy radiotherapy is the new standard for early-stage Hodgkin lymphoma due to lower toxicity and similar effectiveness.
research Original Article: Effectiveness of Steroid Minipulse Therapy for Alopecia Areata
Minipulse therapy with betamethasone effectively promotes hair regrowth in alopecia areata with fewer side effects.
research Original Article: Study on Subclinical Infiltration Patterns of Basal Cell Carcinoma of the Eyelid Using Mohs Micrographic Surgery
Oral minipulse therapy with betamethasone effectively promotes hair regrowth in alopecia areata with fewer side effects.
research Replicative Stress, Stem Cells, and Aging
Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
research The Increasing Incidence of Frontal Fibrosing Alopecia: In Search of Triggering Factors
Various potential triggers may be causing the rise in frontal fibrosing alopecia, and avoiding these could help stop the disease's increase.
research Frontal Fibrosing Alopecia: A Disease That Remains Enigmatic
Frontal fibrosing alopecia is a poorly understood condition with increasing cases and unclear treatment effectiveness.
research Clinicopathological Characteristics and Treatment Outcomes of Fibrosing Alopecia in a Pattern Distribution: A Retrospective Cohort Study
Early treatment of fibrosing alopecia in a pattern distribution may improve outcomes.
research Non-Clinical Safety Evaluation and Risk Assessment of Aleglitazar, a Dual PPAR α/γ Agonist, and Its Major Human Metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
research Rare Cutaneous Side Effects of Imiquimod: A Review on Its Mechanisms, Diagnosis, and Management
Imiquimod can cause rare skin side effects, some irreversible, and long-term follow-up is important for users.
research Puberty
The document concludes that pediatricians play a vital role in supporting adolescents through puberty and should enhance their competence in this area.
research Frontal Fibrosing Alopecia Treatment Options
Combination therapy, especially with finasteride, is effective for treating frontal fibrosing alopecia.
research Spectrum of Mucocutaneous Manifestations in HIV-Infected Patients and Its Correlation with CD4 Lymphocyte Count
HIV patients with lower CD4 T cell counts often have more skin problems.
research Oral Zinc Sulphate in Treatment of Patients with Thallium Poisoning: A Clinical Therapeutic Trial
Oral zinc sulphate is an effective and safe treatment for thallium poisoning.
research Management of Alopecia Areata: Updates and Algorithmic Approach
New treatments for alopecia areata show promise, but no cure exists and responses to treatments vary.
research ULBP3: A Marker for Alopecia Areata Incognita
ULBP3 could be a marker for diagnosing alopecia areata incognita and may be linked to its cause and development.
research Response to Effectiveness of Dutasteride in a Large Series of Patients with Frontal Fibrosing Alopecia in Real Clinical Practice
The authors suggest that 5-α-reductase inhibitors, like dutasteride, are effective in treating frontal fibrosing alopecia and should be the first-line treatment, with other options for severe cases. They also recommend further research on Janus kinase inhibitors.
research Moth-Eaten Alopecia as a Manifestation of Various Skin Diseases: Reporting a Series of 100 Cases
Moth-eaten alopecia is linked to various skin diseases and requires early treatment to prevent worsening.
research Cicatricial Alopecia: Early Diagnosis and Treatment Strategies
Early diagnosis and aggressive treatment are crucial for Cicatricial Alopecia, and treatment effectiveness varies among patients.
research Frontal Fibrosing Alopecia: Clinical Presentations and Prognosis
FFA is more common in postmenopausal women, can affect younger women, and may stabilize over time.
research Targeting the Hippo/YAP/TAZ Signalling Pathway: Novel Opportunities for Therapeutic Interventions into Skin Cancers
Blocking YAP/TAZ could be a new way to treat skin cancer.
research Optimal Management of Frontal Fibrosing Alopecia: A Practical Guide
Early diagnosis and combination therapy, especially with finasteride and dutasteride, are key to managing Frontal Fibrosing Alopecia effectively.
research Alopecia Areata: A Review of Diagnosis, Pathogenesis, and the Therapeutic Landscape
New treatments for alopecia areata show promise, but standardized guidelines are needed.
research Alopecia
The document concludes that alopecia has various forms, each with specific treatments, but no definitive cure for certain types like CCCA has been proven.
research News in Brief
Researchers found potential new targets for treating melanoma and nonmelanoma skin cancers, and identified a possible cause and treatment for male pattern baldness and eczema.
research Post-Menopausal Frontal Fibrosing Alopecia
The document concludes that post-menopausal frontal fibrosing alopecia is a poorly understood condition that does not respond well to common treatments.