Hair Loss: A Harbinger of Morbidities to Come

    Dilip Gude
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    TLDR Early hair loss in men and women may indicate a higher risk of heart disease and metabolic problems.
    The document discusses the association between male pattern hair loss (MPH) and various health conditions, particularly coronary artery disease (CAD) and metabolic syndrome. It highlights that early-onset androgenetic alopecia (AGA) is a risk factor for early severe heart disease and that individuals with early AGA are at an increased risk for coronary revascularization procedures. Women with markers of insulin resistance also have a significantly increased risk for female AGA, which is linked to a higher prevalence of metabolic syndrome. The document cites studies showing higher rates of hypertension, diabetes, and hyperinsulinemia among men with AGA compared to those with normal hair status. It also notes that CAD patients tend to have more significant hair loss and that certain patterns of baldness, such as vertex balding, are associated with a higher risk of CAD, especially in men with hypertension or high cholesterol. The pattern of hair loss is suggested as a clinical indicator for clinicians to assess the risk of diseases, particularly CAD and metabolic syndrome.
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