245 citations,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
9 citations,
March 2019 in “Science” Blocking cell death in certain stem cells can improve wound healing and tissue regeneration.
1 citations,
January 2013 in “Journal of Investigative Dermatology” The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
14 citations,
January 2013 in “Journal of Cutaneous Medicine and Surgery” Some cancer treatments can cause permanent hair loss.
15 citations,
April 2017 in “Cell Stem Cell” Some brain cancer cells avoid immune system detection, and certain treatments could target this to slow their growth; also, certain fat cell precursors help regenerate hair and skin after injury.
10 citations,
November 2010 in “Pigment Cell & Melanoma Research” Only skin melanocytes, not other types, can color hair in mice.
77 citations,
July 2012 in “Journal of Investigative Dermatology” Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.
September 2023 in “Nature Communications” Immune cells are essential for skin regeneration using biomaterial scaffolds.
14 citations,
November 2005 in “Life sciences” Vitamin D3 may protect rat hair follicles from radiation damage.
January 2020 in “Archives of Medicine and Health Sciences” Certain immune molecules and stress affect hair loss, and while genes play a role, more research is needed to fully understand and treat it.
2 citations,
June 2023 in “Gels” Injectable hydrogels are becoming increasingly useful in medicine for drug delivery and tissue repair.
13 citations,
September 2019 in “EBioMedicine” sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.
88 citations,
December 2018 in “Advanced Healthcare Materials” Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.
April 2018 in “Journal of Investigative Dermatology” Different types of stem cells in the skin contribute to the variety of melanoma forms.
April 2016 in “Journal of Investigative Dermatology” The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.
3 citations,
April 2016 in “Dermatologic Surgery” A man's forehead and eyebrow were successfully reconstructed with a skin and hair graft that matched his other eyebrow, without needing frequent trimming.
61 citations,
April 1969 in “Archives of Dermatology” Skin biopsy is crucial for diagnosing unknown baldness causes.
17 citations,
June 2017 in “British Journal of Dermatology” The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.
72 citations,
November 2017 in “Journal of developmental biology” The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Elf5 is important for skin stem cell growth and could help treat skin and hair problems.
2 citations,
September 2021 in “Journal of Pathology of Nepal” Most skin cysts were common types found in unusual body parts, and examining tissue samples is important for accurate diagnosis.
32 citations,
January 2014 in “Cells tissues organs” Hair follicle stem cells can help repair nerve and spinal cord injuries.
12 citations,
May 2023 in “EMBO reports” High mTORC1 activity slows hair growth and causes it to lose color.
6 citations,
June 2020 in “Journal of Drugs in Dermatology” PRP can help regrow hair in people with alopecia.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
52 citations,
May 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” Parathyroid hormone-related protein helps control hair growth phases in mice.
19 citations,
January 2007 in “Biological & pharmaceutical bulletin” Glycine reduces skin pigmentation by lowering melanin production.
January 2023 in “Pharmaceutics” AA–TF#15 significantly promotes hair regrowth and could be an effective treatment for androgenic alopecia.
Stem cells can improve skin grafts by enhancing blood flow and hair growth.
48 citations,
January 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Chemokine signaling is important for hair development.