April 2017 in “Journal of Investigative Dermatology” The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.
29 citations,
May 2020 in “npj Regenerative Medicine” Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
17 citations,
February 2019 in “PubMed” Stem cells can help regenerate hair follicles.
April 2018 in “Journal of Investigative Dermatology” Blocking a specific immune cell signal can trigger hair growth.
28 citations,
March 2016 in “Toxicologic pathology” Dogs could be good models for studying human hair growth and hair loss.
26 citations,
April 2011 in “Skin Research and Technology” In vivo confocal scanning laser microscopy is an effective, non-invasive way to study and measure new hair growth after skin injury in mice.
January 2017 in “Springer eBooks” Scientists made working hair follicles using stem cells, helping future hair loss treatments.
829 citations,
May 2007 in “Nature” Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
759 citations,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
59 citations,
March 2020 in “Journal of Biomedical Science” Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
22 citations,
October 2018 in “Aesthetic Plastic Surgery” Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.
19 citations,
August 2019 in “Expert Opinion on Therapeutic Targets” New treatments for hair loss may target specific pathways and generate new hair follicles.
17 citations,
June 2020 in “Animals” lncRNAs may regulate hair follicle development in Hu sheep.
8 citations,
May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
April 2017 in “Journal of Investigative Dermatology” Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.
1 citations,
March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
July 2022 in “Research Square (Research Square)” Certain miRNAs may play a role in sheep hair follicle development, which could help improve wool production.
November 2023 in “npj regenerative medicine” Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
April 2017 in “Journal of Investigative Dermatology” Blocking JAK-STAT5 signaling in mice leads to hair growth.
16 citations,
December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Sweat gland development involves two unique skin cell programs and a temporary skin environment.
2 citations,
September 2023 in “PLoS biology” Newly divided skin cells quickly move to join skin structures due to tissue tension and specific signals.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Dermal EZH2 controls skin cell growth and differentiation in mice.
April 2017 in “Journal of Investigative Dermatology” Certain microRNAs may protect against hair loss in alopecia areata and could be potential treatment targets.
5 citations,
December 2021 in “Journal of Investigative Dermatology” Hedgehog signaling in certain cells is crucial for hair growth during wound healing.
May 2023 in “Frontiers in Cell and Developmental Biology” The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.
26 citations,
January 2007 in “Organogenesis” Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.
5 citations,
October 2022 in “BMC genomics” Certain microRNAs are important for sheep hair follicle development and could help improve wool quality.
January 2022 in “Stem cell biology and regenerative medicine” iPSCs could help develop treatments for hair loss.
16 citations,
April 2021 in “Frontiers in Cell and Developmental Biology” New hair follicles could be created to treat hair loss.