61 citations,
September 2010 in “Genomics” The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
50 citations,
March 2001 in “Clinics in dermatology” Human hair is complex and grows in cycles starting from embryonic life.
34 citations,
December 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” Rat vibrissa follicles are useful for studying hair growth cycles, especially the transition from pro-anagen to anagen.
18 citations,
March 2003 in “PubMed” Hair loss in women can be due to abnormal hair growth cycles or damaged hair follicles, with the most common type being androgenetic alopecia; treatment varies by cause, and the psychological impact is significant.
April 2024 in “Communications biology” Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.
55 citations,
March 2010 in “Aging” Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.
6 citations,
March 2019 in “The American Journal of Dermatopathology” Amyloid deposits linked to a type of protein may cause a unique pattern of hair loss by disrupting hair growth cycles.
May 2012 in “CRC Press eBooks” Different types of hair loss within Telogen Effluvium are caused by various disruptions in hair growth cycles.
January 2017 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu” Mice with a changed Hr gene lose and regrow hair due to changes in the gene's activity.
89 citations,
September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
2 citations,
May 2020 in “Giornale italiano di dermatologia e venereologia” Vitamin D and its receptor are important for hair and scalp health and may help treat hair loss.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
Different hair growth phases affect how follicles respond to X-rays, and hormones like testosterone and dihydrotestosterone play a key role in baldness; transplanted hair can grow on bald scalp areas.
81 citations,
December 2009 in “Journal of Dermatological Science” Fat tissue stem cells may help increase hair growth.
32 citations,
August 2015 in “Journal of Investigative Dermatology” Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.
19 citations,
May 2004 in “The American Journal of Dermatopathology” The research found that a specific gene mutation causes fewer hair follicles and disrupted hair growth cycles, leading to thin and short hair in people with Hypotrichosis with Juvenile Macular Dystrophy.
65 citations,
January 2018 in “Nature Reviews Endocrinology” Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
86 citations,
October 2005 in “Experimental Dermatology” The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
28 citations,
January 2007 in “Dermatology” Chemotherapy can cause rapid, extensive hair loss, with patterns varying between individuals.
5 citations,
November 2020 in “EBioMedicine” Disruptions in sleep-wake cycles can cause health problems like mental, metabolic, and heart diseases, and cancer.
January 2010 in “China Animal Husbandry & Veterinary Medicine” RORs may influence cashmere growth cycles.
6 citations,
December 2011 in “Nature” The circadian clock in skin cells controls their growth and rest cycles.
4 citations,
July 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” BLMP-1 is important for regular molting and gene expression cycles in worms.
29 citations,
February 1987 in “General and comparative endocrinology” Thyroid and gonadal hormones control seasonal hair growth and molting in male European badgers.
40 citations,
December 2004 in “Dermatology” Kenogen increases with hair loss in women.
13 citations,
June 2020 in “BMC genomics” A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.
4 citations,
October 2018 in “Cell Stem Cell” Hox genes control hair growth patterns in mammals by regulating stem cell activity in the skin.
January 2018 in “Springer eBooks” Telogen effluvium is hair loss caused by disruption of the normal hair cycle.
November 2008 in “Medical Hypotheses” The conclusion suggests a new treatment for infantile hemangiomas and a potential target for hair loss treatment.
1 citations,
January 2018 in “Springer eBooks” The document concludes that scalp cooling and treatments like minoxidil can help manage hair loss from cancer therapy.