125 citations,
September 2001 in “The FASEB Journal” Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.
36 citations,
February 2018 in “British Journal of Dermatology” Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.
57 citations,
March 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
46 citations,
March 2019 in “Journal of Pineal Research” Melatonin improves cashmere goat hair growth and quality by increasing antioxidants and reducing cell death.
8 citations,
January 2017 in “Stem Cells International” A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
1 citations,
March 2020 in “Current Science” Most people in the surveyed area experience hair loss, but they are not aware of the role of diet, iron, hormones, genetics, and possibly water quality in causing it.
36 citations,
April 2016 in “British journal of dermatology/British journal of dermatology, Supplement” A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.
137 citations,
September 2005 in “Proceedings of the National Academy of Sciences of the United States of America” The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.
60 citations,
November 2013 in “Development” Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.
36 citations,
May 2016 in “Biomaterials” Endo-HSE helps grow hair-like structures from human skin cells in the lab.
14 citations,
March 2017 in “Plastic and reconstructive surgery. Global open” Hair follicle damage happens during hair transplants and can impact success; better surgical methods are needed.
7 citations,
October 2000 in “Allergo Journal” Stress may affect hair growth by influencing hair follicle development and could contribute to hair loss.
4 citations,
January 2015 in “Experimental Dermatology” Human hair follicle dermal cells can help repair damaged hair follicles.
88 citations,
July 2019 in “International Journal of Molecular Sciences” Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.
7 citations,
June 2015 in “The anatomical record” Hexi cashmere goats' hair growth varies by stage, with Hoxc13 linked to hair activity.
March 2023 in “Clinical, cosmetic and investigational dermatology” IL-33 is linked to hair follicle damage in psoriasis and could be a treatment target for hair loss in this condition.
18 citations,
October 2018 in “Nutrients” Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.
64 citations,
March 2005 in “Journal of Investigative Dermatology” Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
9 citations,
June 2019 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” A specific RNA increases hair stem cell growth and skin healing by affecting a protein through interaction with a microRNA.
5 citations,
October 2021 in “Signal Transduction and Targeted Therapy” Stress hormone corticosterone suppresses hair growth by affecting stem cell activity and Gas6 protein expression.
2 citations,
November 2017 in “Histochemistry and Cell Biology” Polyamines are abundant in certain parts of rat hair follicles and may play a key role in hair growth.
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
277 citations,
February 2013 in “Science Signaling” Mitochondrial reactive oxygen species are essential for skin and hair development.
245 citations,
October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
79 citations,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia areata may be treated by restoring hair follicle immune privilege and adjusting immune responses.
72 citations,
November 2017 in “Journal of developmental biology” The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
67 citations,
December 2008 in “Developmental Biology” Msx2 and Foxn1 are both crucial for hair growth and health.
66 citations,
May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
32 citations,
May 2015 in “Journal of Investigative Dermatology” Mice without collagen VI have slower hair growth normally but faster regrowth after injury.
21 citations,
May 2018 in “Journal of Cosmetic Dermatology” Costunolide helps human hair cells grow and can stimulate hair growth in mice.