research From Genotoxic Stresses to Skin Damage: Distinct, Novel Mechanisms of Skin and Hair Damage in Chemo/Radiation Therapy
Chemotherapy and radiation therapy cause skin and hair damage by altering gene expression and signaling pathways.
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research Hair Follicle Plasticity with Complemented Immune-Modulation Following Follicular Unit Extraction
Transplanted hair follicles can change and adapt to new areas of the body, with the immune system possibly playing a role in this adjustment.
research Hair Shaft Structures in EDAR Induced Ectodermal Dysplasia
The EDAR gene mutation leads to thinner and more deformed hair shafts.
research The Hair Follicle as an Estrogen Target and Source
Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
research Hormone-Related Hair Disorders: From Clinical Needs to New Therapeutic Perspectives
New treatments targeting insulin, blood flow, and inflammation could improve hormone-related hair conditions with fewer side effects.
research Transient Treatment of Pregnant Merino Ewes with Modulators of Cortisol Biosynthesis Coinciding with Primary Wool Follicle Initiation Alters Lifetime Wool Growth
Altering maternal cortisol during pregnancy can improve wool growth in Merino sheep.
research Light-Emitting Hair Follicles: Studying Skin Regeneration With In Vivo Imaging
Scientists developed tools to observe hair regeneration in real time and assess skin health, using glowing mice and light-controlled genes.
research The Wnt-Inhibitor Dkk4 Is Required for Primary Hair Follicle Induction and Patterning
Dkk4 is necessary for the initial development and arrangement of hair follicles.
research Microarray Analysis Reveals Distinct RNA Expression Profiles in Endothelial Progenitor Cells Exposed to Pro-Inflammatory Environment or Oxidized LDL
Different cells affect hair follicle blood vessels, endothelial cells react differently to inflammation and oxidized fats, and prasugrel better protects heart vessels during a procedure than clopidogrel.
research Lineage Potential, Plasticity, and Environmental Reprogramming of Epithelial Stem/Progenitor Cells
Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.
research Stem Cells in the Hair Follicle and Interfollicular Epidermis of Mice Following Topical Application of Fluocinolone Acetonide
Fluocinolone acetonide slows down hair follicle stem cells but speeds up skin cell growth in mice.
research Combination Use of Triamcinolone Acetonide and Immunotherapy as a New Therapeutic Option in Alopecia Totalis
Combining triamcinolone acetonide and immunotherapy can help regrow hair in some alopecia totalis patients.
research Laser Capture Microdissection Reveals Transcriptional Abnormalities In Alopecia Areata Before, During, And After Active Hair Loss
Alopecia areata involves persistent gene abnormalities and immune activity, even in regrown hair, suggesting a risk of relapse.
research Novel Enzymatic Assay Predicts Minoxidil Response in the Treatment of Androgenetic Alopecia
New test predicts if hair loss treatment will work.
research Hair Growth-Promoting Effect of Carthamus Tinctorius Floret Extract
Safflower (Carthamus tinctorius) extract helps hair grow and could be used in hair products.
research Autophagy Is Essential for Maintaining the Growth of a Human Mini-Organ: Evidence from Scalp Hair Follicle Organ Culture
Autophagy is important for human hair growth and health.
research Hair Physiology and Grooming
Hair is complex, varies in type, and plays a big role in attractiveness and culture.
research Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin
Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.
research A Learning Module in Hair Restoration Surgery: A Simple and Economic Method to Learn All Steps of Strip Method of Hair Follicles Harvesting and Implantation
Garg and Garg created an affordable, easy-to-use training program for hair restoration surgery using everyday items, which can teach a technician the basics in 3-4 weeks with two hours of daily practice.
research Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration
Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
research Hair Follicle as a Target of Stress Hormones and Autoimmune Reactions
Stress hormones and autoimmune reactions can cause hair loss.
research Compartmentalized Organization: A Common and Required Feature of Stem Cell Niches?
Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
research Tissue Homeostasis and Regeneration: Human Limitations and Potential
Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
research Immunology of the Human Nail Apparatus: The Nail Matrix Is a Site of Relative Immune Privilege
The nail matrix has a reduced immune response, protecting it from autoimmunity.
research Molecular Elements of the Regulatory Control of Keratin Filament Modulator AHF/Trichohyalin in the Hair Follicle
The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.
research The Vitamin D Receptor Is Required for Mouse Hair Cycle Progression but Not for Maintenance of the Epidermal Stem Cell Compartment
Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.
research 555 Dermal Single-Cell Atlas: A Novel Tool to Explore Fibroblast Heterogeneity
A new tool helps study hair follicle cells to develop better treatments for hair disorders.
research Stem Cell Niches in Mammals
Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.
research LB1010 Ashwagandha-Derived Exosome-Like Nanoparticles Significantly Promote Human Hair Growth Ex Vivo and In Vivo by Stimulating the Production of the Anagen Promoting Growth Factor VEGF-A
Ashwagandha nanoparticles help hair grow by increasing a growth factor.
research Annual Convention in the Time of COVID: The 2020 Dermatology Nurses' Association Meeting
The convention discussed various skin conditions and treatments, and highlighted the importance of vaccinations for patients on immune-altering medications.