TLDR New treatments targeting insulin, blood flow, and inflammation could improve hormone-related hair conditions with fewer side effects.
The document discussed the role of hormones in hair follicle function and related disorders such as hair loss, seborrhoea, and hirsutism. Traditional treatments included systemic androgen inhibitors and topical estrogens. Emerging therapies focused on insulin sensitivity (rosiglitazone, metformin), blood flow regulation (minoxidil), and anti-inflammatory compounds. Future research aimed to identify new targets beyond sex steroids, such as components of the POMC-system, and to develop advanced drug delivery systems like microparticles for targeted treatment, potentially reducing side effects and increasing efficacy. The study highlighted the importance of individualized treatment strategies for hormone-related hair disorders.
15 citations
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December 2016 in “Revista Da Associacao Medica Brasileira” Polycystic ovary syndrome is a common hormonal disorder in women, linked to increased risk of metabolic and heart diseases, and needs more research for better understanding and treatment.
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April 2016 in “PubMed” The review found that women using hair loss drugs like finasteride and dutasteride rarely reported sexual side effects.
10 citations
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November 2010 in “Skin therapy letter” Women with PCOS often have acne because of high androgen levels, and the article reviewed how to treat this type of acne.
38 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.
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November 2002 in “Journal of The American Academy of Dermatology” Finasteride improves hair loss in women with hyperandrogenism.
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June 2001 in “PubMed” Finasteride is effective in growing hair and stopping hair loss in men with mild to moderate alopecia.
581 citations
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October 1998 in “Journal of The American Academy of Dermatology” Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.
