Search
for

    Research

    5 / 1000+ results

    Community Join

    5 / 1000+ results

      community Breezula Phase 3 Results enough for maintenance?

       13 upvotes 4 months ago
      Breezula shows promise in stabilizing hair loss and potentially promoting regrowth at the one-year mark, offering hope for those who can't tolerate 5AR inhibitors. Its local targeting of androgen receptors could be a significant advancement if it avoids systemic side effects.

      community Consenus on Kx-826/pyrilutamide vs ru58841

       11 upvotes 2 weeks ago
      KX-826 is considered effective for hair maintenance, with better safety research than RU58841, but lacks positive anecdotes. RU58841 is seen as potentially stronger, but concerns exist about systemic effects; combining anti-androgens with 5AR inhibitors is suggested for better results.

      community Minoxidil is a 5ar inhibitor according to research

       150 upvotes 11 months ago
      Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

      community Non-systemic hair loss stack, is there any hope?

       6 upvotes 3 weeks ago
      A 19-year-old is experiencing hair thinning and has tried various doses of oral and topical finasteride but faced psychological and sexual side effects. They are considering topical anti-androgens like KX826, ketoconazole cream, and RU58841 as alternatives, while others suggest clascoterone and topical dutasteride.

    Learn

    7 / 800 results

      learn Finasteride

      Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically

      learn Neem Oil

      Oil from the neem tree, used in traditional remedies

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn GT20029

      Experimental topical drug designed to break down androgen receptors

      learn Bicalutamide

      • Can bicalutamide stop DHT from shrinking your hair follicles? Bicalutamide blocks androgens at the receptor rather than lowering DHT, and some dermatologists prescribe it off-label for women with pattern hair loss, although its US label says it should not be used in women. The one randomised trial (74 women, 2025) found it added no benefit to oral minoxidil, and the drug needs liver monitoring because its label warns of severe and fatal liver injury; it is contraindicated in pregnancy.

      learn RU58841

      Experimental topical anti-androgen sold as a research chemical