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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

BMP2 and BMP7 have opposite roles in feather formation.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

Lamins are vital for cell survival, organ development, and preventing premature aging.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Hormonal therapies are safe and effective for treating adult women's acne.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

New drugs for heart disease may be developed from molecules secreted by stem cells.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.

Pro-IGF-II improves muscle repair in old mice.

Some chemicals absorbed through the skin can cause serious health problems.

Fine wool sheep have more genes for wool quality, while coarse wool sheep have more for skin and muscle traits.

3D cell-derived matrices improve tissue regeneration and disease modeling.