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The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

A young woman with a rare hair loss condition improved with steroid and biotin treatment.

Minoxidil helps stabilize hair loss, increase density, and reduce shedding after hair transplant surgery.

Homeopathic treatments can effectively manage hair loss and improve well-being.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.

Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.

A gene variant increases the risk of a type of hair loss by affecting hair protein production.

Pregnancy can cause more body and scalp hair growth and make nails brittle, but these changes often revert after giving birth.

Most hair loss in children is caused by a few common conditions and is easy to diagnose, but rare types require careful evaluation.

Freezing gamma-irradiated amniotic fluid may help hair growth and speed up the growth phase.

A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.

Eclipta alba extract helps increase hair growth and decrease hair loss-related protein in mice.

Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Blocking a protein called CXXC5 with a specific peptide can stimulate hair regrowth and new hair growth in wounds.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

Some mutant mice have hair with abnormal cross-linking, mainly in the cuticle, not affecting other hair parts.

Finasteride effectively treats baldness but may cause sexual side effects.

DHT stops hair regrowth in mice, similar to human hair loss.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

A 45-year-old woman with autoimmune diseases experienced patchy hair loss due to alopecia areata, which has no cure but can be treated, with varying success.

Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.

P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.