research Animal Models of Androgen-Dependent Disorders of the Pilosebaceous Apparatus
Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
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research Glutamate Transporter SLC1A3 Mediates Inter-Niche Stem Cell Activation During Skin Growth
The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
research Alopecia in Rhesus Macaques Correlates with Immunophenotypic Alterations in Dermal Inflammatory Infiltrates Consistent with Hypersensitivity Etiology
Hair loss in Rhesus macaques may be caused by a skin allergy-related condition.
research Quorum Sensing and Other Collective Regenerative Behaviors in Organ Populations
Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.
research A Spontaneous Deletion Within the Desmoglein 3 Extracellular Domain of Mice Results in Hypomorphic Protein Expression, Immunodeficiency, and a Wasting Disease Phenotype
A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.
research Two Mouse Mutations Mapped to Chromosome 11 with Differing Morphologies but Similar Progressive Inflammatory Alopecia
Two mouse mutations cause similar hair loss despite different skin changes.
research Hereditary, Congenital, and Acquired Alopecias in Dogs and Cats
The conclusion is that different types of hair loss in dogs and cats can be cosmetic or serious, and affected animals should not be bred.
research Lrig1-Expressing Epidermal Progenitors Require SCD1 to Maintain the Dermal Papilla Niche
Hair growth-related cells need the enzyme SCD1 to help maintain the area that supports hair growth.
research A Review on Nanoparticle-Based Herbal Remedies for the Management of Alopecia
Nanoparticle-based herbal remedies could be promising for treating hair loss with fewer side effects and lower cost, but more research is needed.
research Hereditary, Congenital, and Acquired Alopecias
Different types of hair loss in dogs and cats have various causes and treatments, with outcomes ranging from good to uncertain.
research Cutaneous Epithelial Stem Cells
Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
research A Clinician's Approach to Canine Alopecia
The guide explains how to diagnose and treat hair loss in dogs, covering causes and treatments, with some conditions lacking treatment options.
research A Small Molecule Inhibitor Partitions Two Distinct Pathways for Trafficking of Tonoplast Intrinsic Proteins in Arabidopsis
Two distinct pathways direct proteins to vacuoles in Arabidopsis, affecting root hair growth and protein targeting.
research Pathological Studies of Cross-Related Congenital Hypotrichosis in Cattle
Crossbreeding certain European cattle breeds may cause hair and physical issues in cattle.
research Cutaneous Markers of Disorders Affecting Adult Horses
Skin and hair changes in horses can indicate serious diseases, and recognizing these signs is important for treatment and management.
research Study of the Behavior of Lesional and Nonlesional Skin of Canine Recurrent Flank Alopecia Transplanted to Athymic Nude Mice
Dog skin with hair loss, when transplanted to mice, regrew hair, suggesting the hair loss cause is likely body-wide, not skin-specific.
research Ascorbigen Induces Dermal Papilla Cell Proliferation In Vitro, But Fails To Modulate Chemotherapy-Induced Alopecia In Vivo
Ascorbigen increases hair cell growth in a lab setting but does not prevent hair loss from chemotherapy in mice.
research Hypotrichosis Congenita (KRT71 Mutation) in Hereford Cattle in Uruguay
A KRT71 mutation in Hereford cattle in Uruguay causes thin, curly hair and scaly skin.
research The Development of Several Organs and Appendages Is Impaired in Mice Lacking Sp6
Mice without the Sp6 gene have problems developing several body parts, including hair, teeth, limbs, and lungs.
research Cicatricial Alopecia Research Foundation Meeting, May 2016: Progress Towards the Diagnosis, Treatment, and Cure of Primary Cicatricial Alopecias
The meeting focused on understanding, diagnosing, and finding treatments for irreversible hair loss diseases.
research Skin-Specific Expression of a Truncated E1a Oncoprotein Binding to p105-Rb Leads to Abnormal Hair Follicle Maturation Without Increased Epidermal Proliferation
The oncoprotein causes abnormal hair growth without increasing skin cancer risk.
research Intragenic Deletion in the Desmoglein 4 Gene Underlies the Skin Phenotype in the Iffa Credo Hairless Rat
A gene deletion causes the "hairless" trait in Iffa Credo rats.
research Genome-Wide Detection of RNA Editing Events During the Hair Follicles Cycle of Tianzhu White Yak
RNA editing significantly affects hair growth and follicle cycling in the Tianzhu white yak.
research SIRT7 Activates Quiescent Hair Follicle Stem Cells to Ensure Hair Growth in Mice
SIRT7 protein is crucial for starting hair growth in mice.
research Bioengineering the Hair Follicle
Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.
research Novel Insights Into the Pathways Regulating the Canine Hair Cycle and Their Deregulation in Alopecia X
The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.
research HGF/SF Increases Number of Skin Melanocytes but Does Not Alter Quality or Quantity of Follicular Melanogenesis
HGF/SF increases skin melanocytes but doesn't change melanin type or amount.
research EGFR Controls Hair Shaft Differentiation in a p53-Independent Manner
EGFR helps control how hair grows and forms without needing p53 protein.
research The Anti-Apoptotic Bcl-2 Protein Regulates Hair Follicle Stem Cell Function
The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.
research Klhl24-Mediated Hair Follicle Stem Cells Structural Disruption Causes Alopecia
A faulty KLHL24 gene leads to hair loss by damaging hair follicle stem cells.