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DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

The Pemphigus Disease Area Index and Autoimmune Bullous Skin Disorder Intensity Score are the best tools for assessing pemphigus severity.

Epigenetic changes are crucial for hair follicle stem cells to function properly.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

Epigenetic mechanisms control skin development by regulating gene expression.

Exosomes could be a promising way to help repair skin and treat skin disorders.

Studying premature aging syndromes helps understand human aging and suggests potential treatments.

Ezh2 controls skin development by balancing signals for dermal and epidermal growth.

Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

Histone modification is key in treating chronic inflammatory skin diseases.

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

Dermal EZH2 controls skin cell growth and differentiation in mice.

Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.

Stem cell self-renewal is complex and needs more research for full understanding.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.

Dermal EZH2 controls skin cell development and hair growth in mice.

Lamins are vital for cell survival, organ development, and preventing premature aging.

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Metabolism plays a key role in determining stem cell fate.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.