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Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

NIPP1 is important for healthy skin and could help treat skin inflammation.

The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.

The Pemphigus Disease Area Index and Autoimmune Bullous Skin Disorder Intensity Score are the best tools for assessing pemphigus severity.

Epigenetic changes are crucial for hair follicle stem cells to function properly.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

Histone modification is key in treating chronic inflammatory skin diseases.

Ezh2 controls skin development by balancing signals for dermal and epidermal growth.

Dermal EZH2 controls skin cell growth and differentiation in mice.

The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.

Studying premature aging syndromes helps understand human aging and suggests potential treatments.

Exosomes could be a promising way to help repair skin and treat skin disorders.

Epigenetic mechanisms control skin development by regulating gene expression.

Stem cell self-renewal is complex and needs more research for full understanding.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Lamins are vital for cell survival, organ development, and preventing premature aging.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Dermal EZH2 controls skin cell development and hair growth in mice.

Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.