34 citations,
July 2018 in “American Journal of Physiology-heart and Circulatory Physiology” Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.
34 citations,
February 1993 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
32 citations,
January 2021 in “Molecules” Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.
32 citations,
March 2013 in “Journal of Pharmaceutical Sciences” Iontophoresis improves minoxidil delivery for alopecia treatment.
31 citations,
January 2011 in “Dermato-endocrinology” Melatonin protects skin against UV damage by regulating various cellular processes.
26 citations,
February 2009 in “Drug Development Research” 17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
26 citations,
June 1983 in “Journal of Hypertension” Minoxidil lowers blood pressure more effectively but has more side effects, so try hydralazine first.
25 citations,
June 1990 in “Journal of Pharmaceutical Sciences” Longer contact time increases minoxidil absorption, but doesn't affect metabolism.
23 citations,
June 1996 in “Toxicology” Older rats more affected by minoxidil's cardiotoxic effects than younger rats.
22 citations,
June 2012 in “PLOS ONE” Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
20 citations,
October 2018 in “Physics and chemistry of liquids” Minoxidil dissolves better in ethanol-water mixtures at different temperatures, with water playing a key role.
16 citations,
May 2019 in “International Journal of Women's Dermatology” The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.
16 citations,
October 2014 in “Oral surgery, oral medicine, oral pathology and oral radiology” Keratoacanthoma comes from hair follicle cells.
12 citations,
July 2014 in “Journal of Investigative Dermatology” Chemotherapy causes complex changes in hair follicle cells that can lead to hair loss.
The new treatment regimen was effective in promoting significant hair growth in all 15 male patients with androgenic alopecia.
8 citations,
October 2022 in “Regenerative Therapy” New regenerative treatments for hair loss show promise but need more research for confirmation.
7 citations,
March 2021 in “Biology” Scaffold improves hair growth potential.
6 citations,
May 2021 in “Aesthetic Surgery Journal” Higher cell number PRP improves hair density and diameter more than lower cell number PRP.
6 citations,
September 2019 in “Journal of Cosmetic Dermatology” Laser treatment effectively increases hair density and thickness in androgenic alopecia.
5 citations,
December 2022 in “Annals Academy of Medicine Singapore” Some skin medications can have harmful interactions with the COVID-19 drug nirmatrelvir-ritonavir, but not with molnupiravir.
3 citations,
May 2021 in “Archiv der Pharmazie” SUN11602 and ONO-1301 could help in skin healing and creating artificial skin.
2 citations,
May 2023 in “Plants” Allium hookeri extract may help promote hair growth and protect cells from damage.
1 citations,
March 2024 in “Journal of Cellular and Molecular Medicine” 4-octyl itaconate may prevent hearing loss caused by the drug cisplatin by activating certain cell protection pathways.
March 2024 in “Asian journal of beauty & cosmetology” Derma Genie™-H001 can help prevent hair loss and promote hair growth.
January 2024 in “Scientific reports” Egyptian Mint effectively kills mosquito larvae and inhibits certain bacteria.
53 citations,
October 2012 in “The FASEB Journal” Bimatoprost, a glaucoma medication, may also help treat hair loss.
11 citations,
June 2012 in “Human Reproduction Update” The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.
The KRTAP36-2 gene in sheep affects wool yield.
83 citations,
April 1992 in “Clinical Endocrinology” Having enough iron improves the effectiveness of a specific hair loss treatment in women.
7 citations,
July 2019 in “Animals” The KRTAP21-1 gene affects wool yield and can help improve wool production.