Search

everythinglearnresearchcommunity

for

Search:↓

Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Stem cell self-renewal is complex and needs more research for full understanding.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Pannexin 3 is important for bone formation and the development of bone cells.

Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.

Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Arctiin helps protect hair cells from damage and death caused by oxidative stress.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.

Baicalin helps hair growth by activating specific cell signals and pathways.

Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.