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    Glossary Growth Factor Antagonist

    substance that blocks proteins promoting cell growth

    A Growth Factor Antagonist is a substance that inhibits the action of growth factors, which are proteins that stimulate cell growth, proliferation, and differentiation. By blocking these signals, growth factor antagonists can slow down or stop processes like tissue regeneration or tumor growth, making them useful in treatments for conditions like cancer or excessive scarring.

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    1. Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice Cancer Research · 2009 · 53 citations
    2. Data from Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice 2023
    3. Data from Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice 2023
    4. An epidermis‐permeable dipeptide is a potential cosmetic ingredient with partial agonist/antagonist activity toward fibroblast growth factor receptors Journal of Cosmetic Dermatology · 2019 · 3 citations
    5. 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells 2002 · 18 citations
    6. Dihydrotestosterone inhibits hair growth in mice by inhibiting insulin-like growth factor-I production in dermal papillae Growth Hormone & IGF Research · 2024 · 32 citations
    7. Corticotropin-Releasing Factor Down-Regulates Hair Growth-Related Cytokines in Cultured Human Dermal Papilla Cells Journal of the Society of Cosmetic Scientists of Korea · 2014 · 1 citations
    8. Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression (Catagen) by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla Journal of Investigative Dermatology · 2005 · 92 citations
    9. Development of an aequorin-based assay for the screening of corticotropin-releasing factor receptor antagonists Journal of the Korea Academia-Industrial cooperation Society · 2015
    10. Hair growth inhibition by psychoemotional stress: a mouse model for neural mechanisms in hair growth control Experimental Dermatology · 2005 · 127 citations
    11. 839 Spatiotemporal antagonism in mesenchymal-epithelial Signaling in sweat versus hair fate decision Journal of Investigative Dermatology · 2017
    12. Skin toxicity caused by EGFR antagonists—An autoinflammatory condition triggered by deregulated IL‐1 signaling? Journal of Cellular Physiology · 2008 · 19 citations
    13. Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot Developmental biology · 2003 · 243 citations
    14. Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology Journal of Investigative Dermatology · 2003 · 176 citations
    15. An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice ( <i>Acomys</i> ) Science Advances · 2023 · 1 citations
    16. An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice (<i>Acomys</i>) bioRxiv (Cold Spring Harbor Laboratory) · 2022
    17. Hyaluronic acid-FGF2-derived peptide bioconjugates for suppression of FGFR2 and AR simultaneously as an acne antagonist Journal of nanobiotechnology · 2023 · 6 citations
    18. Neurogenic Inflammation in Stress-Induced Termination of Murine Hair Growth Is Promoted by Nerve Growth Factor American Journal of Pathology · 2004 · 108 citations
    19. Trends in the Development of New Drugs for Treatment of Benign Prostatic Hyperplasia Current Medicinal Chemistry · 2006 · 14 citations
    20. Тіе Modern treatment of androgenetic alopecia Vestnik dermatologii i venerologii · 2017
    21. Тіе Modern treatment of androgenetic alopecia DOAJ (DOAJ: Directory of Open Access Journals) · 2017
    22. Scarless wound healing: finding the right cells and signals Cell and Tissue Research · 2016 · 132 citations
    23. Androgenetic alopecia: combing the hair follicle signaling pathways for new therapeutic targets and more effective treatment options Expert Opinion on Therapeutic Targets · 2019 · 19 citations
    24. The local hypothalamic–pituitary–adrenal axis in cultured human dermal papilla cells BMC Molecular and Cell Biology · 2020 · 9 citations
    25. Clinical Snippets Journal of Investigative Dermatology · 2005
    26. Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development Molecular Biology of the Cell · 2018 · 25 citations
    27. Gene Expression Profiling of the Intact Dermal Sheath Cup of Human Hair Follicles Acta dermato-venereologica · 2018 · 11 citations
    28. Pathogenesis and management of TRPV3-related Olmsted syndrome Frontiers in Genetics · 2024
    29. In Vitro Main Pathways of Steroid Action in Cultured Hair Follicle Cells: Vascular Approach Journal of Investigative Dermatology Symposium Proceedings · 1999 · 30 citations
    30. Current Therapeutic Approaches to Chronic Central Serous Chorioretinopathy Türk oftalmoloji dergisi · 2019 · 13 citations