Search

everythinglearnresearchcommunity

for

Search:↓

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Estrogen therapy can reduce skin aging but has cancer risks.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

Vitamin D is important for bones, hair, blood pressure, and breast development.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Targeting the actin cytoskeleton could improve skin healing and reduce scarring.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Testosterone is crucial for development, growth, and various body functions in mammals.

New treatments for male hypogonadism are effective and should be personalized.

Different light affects cell functions and can help treat skin conditions.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Fingerprints form uniquely before birth due to specific genetic pathways and local signals.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Black cumin and its nanoformulations show promise in treating neurodegenerative diseases.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.