research An Accessible Pharmacodynamic Transcriptional Biomarker for Notch Target Engagement
Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.
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research MTurq2-Col4a1 Mouse Model Allows for Live Visualization of Mammalian Basement Membrane Development
The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.
research Androgenetic Alopecia and COVID-19: A Review of the Hypothetical Role of Androgens
Possible link between androgens and COVID-19 severity; more research needed.
research Genome-Wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage
Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.
research Dermatologic Diseases in Ferrets: Comprehensive Review and Treatment
The document concludes that early diagnosis and treatment are crucial for managing skin diseases in ferrets.
research Function and Underlying Mechanisms of Seasonal Color Molting in Mammals and Birds: What Keeps Them Changing in a Warming World?
Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.
research Aging and Anti-Aging in Hair and Hair Loss
Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
research One of These Things Is Not Like the Others: The Idea of Precedence in Health Technology Assessment and Coverage Decisions
The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.
research IL-33 Contributes to the Pathological Changes of Hair Follicles in Psoriasis: A Potential Target for Psoriatic Alopecia
IL-33 is linked to hair follicle damage in psoriasis and could be a treatment target for hair loss in this condition.
research Marie Unna Hereditary Hypotrichosis: Identification of a U2HR Mutation in the Family from the Original 1925 Report
Researchers found a gene mutation responsible for a rare hair loss condition.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Use of Condensed Nanofat Combined With Fat Grafts to Treat Atrophic Scars
Condensed nanofat with fat grafts effectively improves atrophic facial scars.
research Epithelial-Mesenchymal Interaction in Hair Regeneration and Skin Wound Healing
Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
research Female-Patterned Alopecia in Teenage Brothers with Unusual Histologic Features
Two teenage brothers had a rare, treatment-resistant form of female-pattern hair loss with unusual scalp changes.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
research Montagna Symposium 2017—Precision Dermatology: Next Generation Prevention, Diagnosis, and Treatment
The symposium highlighted the importance of understanding disease mechanisms for targeted dermatology treatments.
research Immune-Mediated Diseases of the Central Nervous System
The document explains the difficulty in diagnosing and treating brain diseases caused by the immune system and stresses the need for quick and accurate tests.
research Blockade of S100A3 Activity Inhibits Murine Hair Growth
Stopping S100A3 activity slows down hair growth in mice.
research The Biology and Clinical Application of Systemic Glucocorticoids
Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
research A Glutathione-Dependent Control of the Indole Butyric Acid Pathway Supports Arabidopsis Root System Adaptation to Phosphate Deprivation
Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.
research Research Progress of Post-Acute Sequelae After SARS-CoV-2 Infection
Long COVID causes various long-term health issues and needs better awareness and treatment.
research Recent Advances in Cellulose Nanocrystals-Based Sensors: A Review
Cellulose nanocrystals are promising for making effective, sustainable sensors for various uses.
research Patient-Reported Burden of Severe Alopecia Areata: First Results from the Multinational Alopecia Areata Unmet Need Survey
Severe alopecia areata greatly impacts quality of life, mental health, and daily activities.
research An Infectious Scalp Disorder: A Case of Gray Patch Tinea Capitis in a 7-Year-Old Girl
A 7-year-old girl's scalp infection was cured with oral medication and medicated shampoo.
research Gray Patch Tinea Capitis Caused by Microsporum Canis
A boy's scalp rash and baldness were cured using oral medication and medicated shampoo.
research Ashy Dermatosis: Treatment with Clofazimine
Clofazimine successfully treated a man's ashy dermatosis, clearing his skin lesions.
research Cortexolone 17a-Propionate: Preclinical Profile of a New Topical, Skin Selective, Steroidal Antiandrogen
Clofazimine may be effective for treating ashy dermatosis.
research Hypaphorine, an Indole-3-Acetic Acid Antagonist Delivered by the Ectomycorrhizal Fungus Pisolithus Tinctorius, Induces Reorganization of Actin and the Microtubule Cytoskeleton in Eucalyptus Globulus ssp. Bicostata Root Hairs
Hypaphorine from a fungus changes the internal structure of Eucalyptus root hairs, stopping their growth.
research Permanent Localized Hair Repigmentation Following Herpes Zoster Infection
Herpes zoster infection can cause permanent hair color change in the affected area.
research A Note on Postinflammatory Hair Darkening
Hair can darken after inflammation and then return to its original color.