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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

Melatonin may help treat PCOS symptoms in rats.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Mobile phone radiation can cause DNA damage in human hair root cells.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.