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Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

The 2023 guideline advises a detailed approach for PCOS, focusing on early detection, lifestyle and medical treatments, and managing health risks.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

OCT4 helps granulosa cell growth in early-stage follicles, and FSH increases OCT4 through specific pathways.

Neurosteroids show promise for treating epilepsy and more research is needed.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

GnRH analogue can help diagnose ovarian causes of high testosterone in postmenopausal women when scans don't show the cause.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

Transgender patients in critical care need better-trained medical staff and specific guidelines.

Deslorelin may help intact male dogs regrow hair from alopecia X, with a 75% success rate and no side effects.

Deslorelin implants successfully treated hair loss in two male Keeshonden dogs.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.

Balancing treatment effectiveness with side effects is crucial for relapsed follicular non-Hodgkin's lymphoma, especially in older patients.

PCOS is a complex condition linked to hormonal imbalance and insulin resistance, with weight loss being important for management.

Effective management of PCOS includes lifestyle changes, medication for menstrual regulation, fertility treatments, and cosmetic issue remedies.

Different PCOS subgroups have similar metabolic features, but those without menstrual problems have milder issues.

Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Flutamide works better than finasteride for hirsutism, and combining both is slightly better but not much.

About 15% of adolescent girls in a region of India have Polycystic Ovarian Syndrome, which is more common in those born by cesarean, with wisdom teeth, or with central obesity.

Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.