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Goserelin and oestradiol treatment slightly improved hairiness but did not significantly change sebum production or hair characteristics in mildly hirsute women.

Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.

Polycystic ovary syndrome (PCOS) affects about 10% of women, is often linked to obesity and family history, and can cause irregular periods, fertility issues, and other symptoms. It's usually managed with lifestyle changes, weight loss, and medication.

Using GnRHa agonists helps diagnose and treat ovarian hyperthecosis when surgery isn't possible.

Effective treatment for skin issues in women with PCOS includes oral contraceptives, antiandrogens, and other medications and procedures.

Monitoring for adverse effects in clinical treatments is crucial.

Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.

The document covers various male health issues, their causes, treatments, and related conditions.

The document concludes that more research is needed to include new treatments in guidelines for Polycystic Ovary Syndrome (PCOS).

Certain maturity signs appear before and after the first release of sperm in boys.

Spironolactone most effective for hirsutism, but has side effects.

Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.

Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.

The Random Forest algorithm was the most accurate at diagnosing Polycystic Ovarian Syndrome.

The study found three different timing patterns of symptoms in women with premenstrual dysphoric disorder.

Finasteride effectively and safely treats recurrent priapism in children and adolescents with sickle cell disease.

Serenoa repens (saw palmetto) may cause side effects like hot flashes in children and needs more research for safety in pediatric use.

The research found that certain microRNAs are important for human hair growth and health.

Researchers found a new genetic mutation linked to a hair condition in a Japanese boy.

DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.

The endocannabinoid system affects oil production and inflammation in skin cells.

Zinc deficiency disrupts hair growth and cycle, but zinc supplements can fix this.

Hirsutism treatment should focus more on patient needs and quality of life.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.