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The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

The document concludes that PCOS in adolescents is complex and requires comprehensive care to manage its symptoms and associated health risks.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

SHBG binding properties are unchanged in male liver cirrhosis patients.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Zinc deficiency disrupts hair growth and cycle, but zinc supplements can fix this.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Women with nonclassic 21-hydroxylase deficiency can have successful pregnancies through IVF, with certain factors affecting their chances.

Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.

PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.

Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.

New tools show that in fish, NPY increases feeding and somatostatin decreases it.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

Finasteride exposure harms tadpole reproduction and hormone balance.

Possible link between androgens and COVID-19 severity; more research needed.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.