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Insulin resistance linked to obesity may increase COVID-19 severity.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Skin problems are common and important signs of eating disorders and treating the eating disorder can improve these skin conditions.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

Hair loss treatments work better with lifestyle changes.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

High levels of androgens during early development may cause PCOS-like symptoms.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Hormonal therapies are safe and effective for treating adult women's acne.

Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.

Women with PCOS often have mood disorders and a lower quality of life, and treatment should focus on both physical and mental health.

Oral contraceptives can cause skin issues like dark patches, acne, yeast infections, sensitivity to light, spider veins, skin rashes, and hair loss.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.

Eating disorders can cause skin problems that need treating the underlying condition for better health.

Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.