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The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.

Different types of dog hair loss are linked to problems starting the hair growth phase and early hair cycle ending.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

Skin problems from transplant drugs are common and need careful management in organ transplant patients.

Young women with nonclassic congenital adrenal hyperplasia may experience worse sexual function and mild depression compared to healthy women.

Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Human hair protein modifications could potentially indicate heart disease risk.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.