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Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Adult acne is often related to hormonal disorders, especially in women, and may need long-term treatment involving specialists.

People with alopecia areata may have a higher risk of blood clots.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

Local testosterone treatment improved sexual desire in a female with fragile X syndrome.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

Accurate diagnosis and tailored treatments are crucial for managing hair loss in humans and animals.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

A patient with Satoyoshi syndrome improved with a treatment combining several medications, including carbamazepine and methotrexate.

Hirsutism is too much hair growth in women like the pattern in men, often caused by high male hormones, and can be treated with hormone control and hair removal methods.

Women with nonclassic congenital adrenal hyperplasia experience more sexual dysfunction and distress.

Sebum production varies by individual and is influenced by age, gender, and hormones, affecting skin and hair health.

Women with nonclassical congenital adrenal hyperplasia may have a higher risk of fertility issues and miscarriages, and should get genetic counseling.

Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.

Adequate steroid treatment needed to limit bone loss in PMR patients.

Hashimoto thyroiditis is an autoimmune disease that can lead to an underactive thyroid and is treated with medication and sometimes diet changes or surgery.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.