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Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Antiandrogen therapy helps treat genetic hair loss.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Skin health and diseases are closely linked to metabolic processes.

Copper deficiency may cause hair loss, and treating it could involve nutrition and hormones.

Clascoterone is safe for the heart, even at high doses.

Testosterone therapy can help postmenopausal women with low sexual desire but needs more safety research and should be used with estrogen therapy.

Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.

Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Nerves and chemicals in the body can affect hair growth and loss.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Prolactin slows down hair growth in mice.

Alopecia in captive rhesus macaques is affected by season, sex, age, housing, and stress, with complex links between stress hormones and hair loss.

Androgenetic alopecia linked to COVID-19 severity; drugs reducing androgen receptor activation may help.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.