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Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.

Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.

Dexamethasone increases androgen receptor activity in scalp cells, which might explain stress-related hair loss.

Patients need better information about the risks of long-term steroid use.

Many patients with Giant Cell Arteritis did not follow their steroid treatment plans properly.

Geranium Sibiricum L extract may promote hair growth by increasing growth factors and decreasing inhibitory factors under stress.

A new gene variant causes glucocorticoid resistance in a mother and son.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

The patient likely has Chrousos syndrome, a rare condition causing insensitivity to glucocorticoids, requiring high-dose dexamethasone treatment.

Prairie dogs with fewer neighbors are more stressed but their number of babies isn't affected.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

SGK3 is essential for proper hair growth and health.

Analyzing bear poop helps measure their stress without harming them.

Long-term glucocorticoid use can cause skin problems like easy bruising and poor wound healing, especially at higher doses.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

The glucocorticoid receptor helps protect skin from tumors and other issues.

Untreated congenital adrenal hyperplasia can lead to complications like stroke and needs glucocorticoid treatment.

Treating classic 21-hydroxylase deficiency requires precise glucocorticoid dosing and attention to individual patient needs, with new treatments showing promise.

Metformin can help prevent the side effects of glucocorticoid medications on metabolism.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.