TLDR Long-term glucocorticoid use can cause skin problems like easy bruising and poor wound healing, especially at higher doses.
The study assessed the cutaneous adverse effects (AEs) of glucocorticoids (GCs) in 381 rheumatoid arthritis patients, categorized by their mean daily GC dose over the past 12 months. It found that Cushingoid habitus, easy bruising, skin atrophy, impaired wound healing, and ecchymosis were significantly more frequent in GC users and were dose-dependent. However, abnormal stretch marks, acne, perioral dermatitis, alopecia, and hirsutism were rare and showed no correlation with GC therapy. The study highlighted the importance of considering these AEs when prescribing GCs.
19 citations
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March 2011 in “Cutaneous and Ocular Toxicology” Some chemicals absorbed through the skin can cause serious health problems.
19 citations
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September 2004 in “Reviews in gynaecological practice” Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.
1 citations
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January 2015 in “Side effects of drugs annual” The document concludes that various dermatological treatments and drugs can cause skin reactions and side effects.
23 citations
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February 1979 in “Veterinary Clinics of North America: Small Animal Practice” Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.
9 citations
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January 1997 in “Gynecological Endocrinology” The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
