TLDR Long-term glucocorticoid use can cause skin problems like easy bruising and poor wound healing, especially at higher doses.
The study assessed the cutaneous adverse effects (AEs) of glucocorticoids (GCs) in 381 rheumatoid arthritis patients, categorized by their mean daily GC dose over the past 12 months. It found that Cushingoid habitus, easy bruising, skin atrophy, impaired wound healing, and ecchymosis were significantly more frequent in GC users and were dose-dependent. However, abnormal stretch marks, acne, perioral dermatitis, alopecia, and hirsutism were rare and showed no correlation with GC therapy. The study highlighted the importance of considering these AEs when prescribing GCs.
19 citations,
March 2011 in “Cutaneous and Ocular Toxicology” Some chemicals absorbed through the skin can cause serious health problems.
19 citations,
September 2004 in “Reviews in gynaecological practice” Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.
1 citations,
January 2015 in “Side effects of drugs annual” The document concludes that various dermatological treatments and drugs can cause skin reactions and side effects.
40 citations,
July 2007 in “Dermatologic Therapy” Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.
24 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
