23 citations
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January 1985 in “Journal of Neuropathology & Experimental Neurology” This study found that cupric chloride treatment may partially correct delayed maturation and abnormal arborization of Purkinje cells in the cerebellum of hemizygous brindled mice, a model for Kinky hair disease.
June 2013 in “Institutional Repositories DataBase (IRDB)” This study reported that Glechoma hederacea subsp. grandis extract promoted hair growth in humans and mice, suggesting its potential as a natural remedy for hair loss conditions.
August 2026 in “Journal of Ayurveda and Integrated Medical Sciences” In this study, dried Gambhari fruit extract was found to increase cell viability and growth of human follicle dermal papilla cells in vitro, showing potential hair growth-promoting activity comparable to Minoxidil 5% at selected concentrations.
October 2022 in “International journal of pharmaceutical sciences review and research” This study compared the antioxidant and antidiabetic activities of Hibiscus rosa-sinensis leaf extract and Eclipta alba bark extract, finding that Hibiscus rosa-sinensis exhibited greater antidiabetic activity, whereas Eclipta alba demonstrated stronger antioxidant activity.
In this study, researchers used an integrated in silico approach to demonstrate that Polygonum multiflorum combats androgenetic alopecia via anthraquinone emodin, which targets PI3K catalytic subunits differently from traditional antiandrogenic treatments, showing potential as a novel therapeutic strategy.
2 citations
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January 2018 in “Dermatology Online Journal” This report describes a case of a 60-year-old woman experiencing inflammatory skin reactions after consuming ginseng and reviews the characteristics of its use in healthcare, although detailed descriptions of such effects are limited.
This study reviewed existing literature and found that green tea may have potential as a treatment for male androgenetic alopecia, demonstrating hair growth stimulation and fewer adverse reactions compared to minoxidil, despite being used in smaller concentrations.
6 citations
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August 2022 in “Journal of Herbal Medicine” In this study, mangosteen pericarp water extract was found to significantly promote hair dermal papilla cell proliferation and enhance melanin synthesis in vitro, surpassing known melanogenic agents such as α-melanocyte stimulating hormone and forskolin in potency.
This study found that teak leaf extract can be effective in promoting hair growth in males with androgenic alopecia; however, significant variability in steroid 5-alpha reductase inhibitory activity among samples from different geographic origins means quality control is important for consistent therapeutic potential.
4 citations
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September 2025 in “International Journal of Molecular Sciences” This review discusses the dermatological applications and potential health benefits of Epigallocatechin-gallate (EGCG) from green tea, but provides no new clinical findings.
7 citations
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January 2017 in “Biological & Pharmaceutical Bulletin” This study found that polyacetylene compounds in Panax ginseng extracts may inhibit neurotrophin receptor binding, suggesting potential therapeutic benefits for alopecia and other hair growth disorders.
October 2025 in “Interdiciplinary Journal and Hummanity (INJURITY)” This study characterized bioactive compounds in extracts from six Kalimantan herbal plants, confirming traditional medicinal uses with findings such as triterpenoids and several potent compounds with antimicrobial and cardiovascular benefits, laying groundwork for potential therapeutic applications and conservation efforts.
1 citations
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August 2016 in “Hanbang an'i'bi'in'hu pibu'gwa haghoeji” In this study using lab models, YangHyulEum Gami-Bang (YHEG) was associated with promoting hair growth and inhibiting factors that contribute to hair loss.
This study found that the Padina arborescens extract and its component MOGG may prevent hair loss by inhibiting 5α-reductase activity, promoting cell proliferation, opening the KATP channel, and increasing PGE2 production in laboratory settings.
3 citations
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December 2016 in “KSBB Journal” This study found that a herbal medicine increased hair growth in a mouse model, showing strong antioxidant activity and similar 5-alpha-reductase inhibition to finasteride without cytotoxicity in human dermal papilla cells.
1 citations
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March 2022 in “Applied Sciences” This study found that fermented red ginseng marc alleviated atopic dermatitis-like symptoms in mice, demonstrating antioxidant and anti-inflammatory effects similar to those of dexamethasone.
2 citations
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February 2022 in “Preprints.org” This study found that fermented red ginseng marc alleviated skin lesions, reduced inflammation, and demonstrated antioxidant effects in an AD-like mouse model, suggesting potential therapeutic applications for atopic dermatitis.
5 citations
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January 2020 in “Current Pharmaceutical Design” This review discusses the various biological activities of Geranium species and concludes that many studies validate their therapeutic properties claimed by traditional medicine, but it presents no new experimental results.
1 citations
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January 2023 in “Journal of Pharmacognosy and Phytochemistry” This study provided detailed anatomical, physico-chemical, and chromatographic analyses to differentiate Dracaena trifasciata from potential adulterants in traditional medicine.
2 citations
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January 2021 in “Applied Chemistry for Engineering” This review discusses the bioactive substances found in native Korean Pinus densiflora and koraiensis and highlights the need for more research on their industrial application, despite known physiological effects.
18 citations
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June 2017 in “Proceedings of the National Academy of Sciences of the United States of America” In this mouse study, hair growth defects associated with the Gk5 null allele were partially alleviated by simvastatin treatment, suggesting GK5 plays a key role in skin-specific cholesterol regulation.
June 2026 in “Journal of Biological Studies” This review synthesizes preclinical evidence suggesting that Centella asiatica may extend healthspan by modulating aging hallmarks, enhancing DNA repair, improving mitochondrial function, and reducing inflammation and oxidative stress, potentially paving the way for future gerotherapeutic strategies.
December 2025 in “International Journal of Molecular Sciences” This study found that an aqueous extract of Bacopa procumbens improved motor function and preserved neuronal structure in a mouse model of Parkinson's disease, suggesting its neuroprotective potential.
January 2024 in “Biochemistry Research International” This study found that compounds from Ziziphus spina-christi roots exhibited promising antibacterial and antioxidant activities, supporting its traditional medicinal use.
November 2024 in “Journal of Investigative Dermatology” Reishi mushroom extract may help treat hair loss.
44 citations
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October 2016 in “Epilepsia” This study demonstrated that the glycolytic inhibitor 2-deoxy-D-glucose enhances antiseizure effects by potentiating extrasynaptic tonic GABAergic inhibition through neurosteroidogenesis in hippocampal slices.
This study found that extract mixtures from certain Chinese herbs promoted hair growth in mice by inducing and prolonging the anagen phase when applied both intragastrically and topically.
October 2024 in “Annals of Dermatology” In this in vitro study, red ginseng extract and its main ginsenoside, G-Rb1, were found to protect human hair follicular keratinocytes from oxidative damage, preventing apoptosis, promoting hair growth, and modulating hair cycle transitions by influencing specific cellular signaling pathways.
June 2025 in “Pharmacon Jurnal Farmasi Indonesia” This systematic review found that mangkokan leaf formulations, especially ethosomal gel or phytosome lotion at 25% concentration, were most effective in stimulating hair growth and improving hair health through various biological mechanisms.