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Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

The document concludes that rib-sparing techniques in breast reconstruction have limited benefits, sentinel lymph node biopsy is needed for desmoplastic melanoma, certain hair preservation methods improve graft survival, partial turbinectomy effectively reduces nasal obstruction, nipple shields with irrigation may reduce capsular contracture, and thicker malignant melanomas have a higher risk of non-skin cancers.

The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.

BMI1 is essential for preventing hair greying and maintaining hair color.

The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

Eribulin-based chemotherapy is more effective and has fewer side effects for advanced triple-negative breast cancer.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

Trichoscopy helps accurately diagnose Netherton syndrome, often mistaken for atopic dermatitis.

Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.

Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.

New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.

Eating isoflavone can help mice grow hair by increasing a growth factor.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Inactive hair follicle stem cells help prevent skin cancer.

Dermal adipose tissue in mice can change and revert to help with skin health.

PCOS may be influenced by factors in the blood, not just the ovaries.

Sheep testis extract significantly improves wound healing and hair growth in rats.

The new chemotherapy combination of WP 631 and Epothilone B shows enhanced effectiveness against ovarian cancer but requires more research on its safety.

Proper niche formation in Drosophila requires Slit-Robo signaling for cell migration.

Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.

Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.

KFSD is a genetic disorder causing hair loss and skin issues, with no effective treatment.

Some leukemia treatments can cause skin reactions similar to keratosis pilaris.

Bmpr2 and Acvr2a receptors are crucial for hair retention and color.