Genetics of Infertility and Assisted Fertilization in the Bible: The Case of Abraham and His Family

The document examines infertility in Abraham's family from a biblical and scientific perspective, suggesting genetic factors like polycystic ovary syndrome (PCOS) or partial 21-hydroxylase deficiency as potential causes. It highlights the stories of Sarah, Rebekah, and Rachel, who overcame infertility through divine intervention, and considers cultural practices like polygamy and surrogacy. The study proposes that infertility may have been transmitted through the male germline, originating from Terach, and draws parallels with modern genetic findings, noting PCOS's prevalence in Mediterranean and Middle Eastern populations. While the narrative suggests divine intervention, the study offers a secular interpretation of these events as "divinely assisted fertilization."