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New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

Minoxidil cream can safely treat hair loss in kids with ectodermal dysplasia.

Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.

Sardinians were historically short due to a mix of genetics and factors like disease and poor nutrition, but recent height increases suggest better living conditions had a bigger impact.

Ethylene and auxin hormones interact in complex ways that are essential for plant growth and development.

Albumin and prednisone improved symptoms in a woman with Cronkhite-Canada syndrome, revealing potential genetic causes.

Early detection and multidisciplinary treatment are crucial for managing Papillon-Lefévre syndrome.

Lipase H is important for hair follicle function and shaping hair fibers.

Dermal Wnt/β-catenin signaling is important for the proper size and development of hair follicles.

The document reviews key historical figures and discoveries in dermatology.

Adult female acne is a complex condition that can worsen with menopause, requiring holistic treatment and tailored skincare at different life stages.

Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.

A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Auxin and ethylene hormones both work together and against each other to control plant growth.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Finasteride effectively blocks enzyme causing male pattern baldness.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Peripilar signs can help diagnose androgenetic alopecia and reveal its cause.

EDA2R gene linked to hair loss.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Wnt10b helps blood stem cells grow after injury.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Live imaging has advanced our understanding of stem cell behavior and raised new research questions.