research Hair Follicle Characteristics as Early Marker of Type 2 Diabetes
Hair characteristics might be early signs of Type 2 Diabetes and could help with early prevention.
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research Skin-Derived Stem Cells as a Source of Primordial Germ Cell and Oocyte-Like Cells
Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.
research Drug Discovery Today: Therapeutic Strategies - 2006 Editorial
The 2006 editorial concluded that immunotherapy was advancing with new drugs, focusing on specific biological therapies and convenient oral treatments, and highlighted the importance of partnerships and new regulations in the field.
research A Study of the Association of Premature Androgenetic Alopecia with Metabolic Syndrome and Coronary Artery Disease
Premature hair loss doesn't increase the risk of metabolic syndrome.
research A Kaleidoscope of Keratin Gene Expression and the Mosaic of Its Regulatory Mechanisms
Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
research Clinical Use of Extracellular Vesicles in the Management of Male and Female Pattern Hair Loss: A Preliminary Retrospective Institutional Review Board Safety and Efficacy Study
Extracellular vesicles may effectively treat hair loss with minimal side effects.
research Toxic Epidermal Necrolysis
Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.
research Hairless Down-Regulates Expression of Msx2 and Its Related Target Genes in Hair Follicles
Hairless protein reduces Msx2 gene activity, affecting hair follicle development.
research Molecular Basis for Hair Loss in Mice Carrying a Novel Nonsense Mutation (Hr^rh-R) in the Hairless Gene (Hr)
A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.
research Cue Masking and Cultural Signals: Testing Context-Specific Preferences for Balding Leaders
Baldness and shaved heads change how traits are seen but don't really affect leader preferences.
research Finasteride Promotes Worsening of the Cardiac Deleterious Effects of Nandrolone Decanoate and Protects Against Genotoxic and Cytotoxic Damage
Finasteride worsens heart damage from nandrolone decanoate but protects against cell damage.
research Rhodococcus Equi: Clinical Manifestations, Virulence, and Immunity
Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.
research Autoimmunity and Autoimmune Co-Morbidities in Psoriasis
Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.
research Human Leukocyte Antigen Class II Alleles Are Associated with Risk of Alopecia Areata
Certain HLA class II alleles increase or decrease the risk of alopecia areata.
research Vitamin D and the Skin: Physiology and Pathophysiology
Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
research What Should It Take to Describe a Substance or Product as 'Sperm-Safe'?
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research The Developing Immune Network in Human Prenatal Skin
Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.
research Mesenchymal Stem Cell-Derived Exosomes for Organ Development and Cell-Free Therapy
MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
research Effects of Altering Allopregnanolone Levels During Critical Neurodevelopmental Periods on Alcohol Consumption Vulnerability
Early NAS level changes affect alcohol consumption vulnerability.
research Hairless and Wnt Signaling: Allies in Epithelial Stem Cell Differentiation
The HR protein's role as a repressor is essential for controlling hair growth.
research Beyond Counting Sheep: Exploring the Link Between Polycystic Ovary Syndrome and Sleep Health
PCOS often leads to sleep problems, especially obstructive sleep apnea, affecting overall health.
research Hair Follicle Targeting with Nanoparticles
Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.
research Beyond Ethnicity in Dermatology
The editor suggests removing "race" and "ethnicity" from dermatology and creating tools to objectively assess skin color and hair texture.
research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Female Hirsutism: Pathophysiological Considerations and Therapeutic Implications
Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
research Past and Future Strategies for GPCR Deorphanization
Finding functions for unknown GPCRs is hard but key for making new drugs.
research Toxoplasma Gondii Infection and Testosterone Alteration: A Systematic Review and Meta-Analyses
Toxoplasma gondii infection may increase testosterone levels in males.
research New Challenge to Cancer and Longevity
A group has developed therapies that show promise for treating cancer and various other conditions.
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research PCOS in Adolescents—Ongoing Riddles in Diagnosis and Treatment
Diagnosing and treating PCOS in teenagers is difficult, and the focus is on lifestyle changes and medication to improve health and prevent future issues.